Precocial rodents as new experimental model to study the effects of altered gravitational conditions on fetal development

Precocial rodents as new experimental model to study the effects of altered gravitational conditions on fetal development

So far the experiments in altered gravitational conditions on the prenatal development have used altricial rodent species. The aim of this study is to explore the differences in the intrauterine development of locomotor system in precocial (guinea pig, spiny mouse) and altricial (rat, mouse, and gol...

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Veröffentlicht in:Microgravity science and technology 2006-09, Vol.18 (3-4), p.223-225
Hauptverfasser: Sekulić, Slobodan, Božić, Ksenija, Bozić, Aleksandar, Borota, Jelena, Ćulić, Milka
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Mammals
Maturity
Mice
Prenatal development
Rodents
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container_end_page 225
container_issue 3-4
container_start_page 223
container_title Microgravity science and technology
container_volume 18
creator Sekulić, Slobodan
Božić, Ksenija
Bozić, Aleksandar
Borota, Jelena
Ćulić, Milka
description So far the experiments in altered gravitational conditions on the prenatal development have used altricial rodent species. The aim of this study is to explore the differences in the intrauterine development of locomotor system in precocial (guinea pig, spiny mouse) and altricial (rat, mouse, and golden hamster) rodent species and to determine which of these mammalian groups represent a better study model to conduct research on the influence of altered gravitational conditions on human fetal development. Findings suggest that the influence of altered gravitational conditions on development of locomotor system significantly vary according to the maturity of mammals. By the characteristics of maturity at birth precocial rodents are more similar to a human than altricial species. Since precocial species have similar maturity of locomotor system to human, the changes caused by altered gravity among them should be similar as opposed to altricial species.[PUBLICATION ABSTRACT]
doi_str_mv 10.1007/BF02870414
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subjects Mammals
Maturity
Mice
Prenatal development
Rodents
title Precocial rodents as new experimental model to study the effects of altered gravitational conditions on fetal development
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