In Vivo Specific Delivery of c-Met siRNA to Glioblastoma Using Cationic Solid Lipid Nanoparticles

RNA interference is a powerful strategy that inhibits gene expression through specific mRNA degradation. In vivo, however, the application of small interfering RNAs (siRNAs) is severely limited by their instability and their poor delivery into target cells and tissues. This is especially true with g...

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Veröffentlicht in:Bioconjugate chemistry 2011-12, Vol.22 (12), p.2568-2572
Hauptverfasser: Jin, Juyoun, Bae, Ki Hyun, Yang, Heekyoung, Lee, Se Jeong, Kim, Hyein, Kim, Yonghyun, Joo, Kyeung Min, Seo, Soo Won, Park, Tae Gwan, Nam, Do-Hyun
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Sprache:eng
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