A Trial of Intrapleural Adenoviral-mediated Interferon-[alpha]2b Gene Transfer for Malignant Pleural Mesothelioma

New therapeutic strategies are needed for malignant pleural mesothelioma (MPM). We conducted a single-center, open-label, nonrandomized, pilot and feasibility trial using two intrapleural doses of an adenoviral vector encoding human IFN-α (Ad.IFN-α2b). Nine subjects were enrolled at two dose levels....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of respiratory and critical care medicine 2011-12, Vol.184 (12), p.1395
Hauptverfasser:	Sterman, Daniel H, Haas, Andrew, Moon, Edmund, Recio, Adriana, Schwed, Daniel, Vachani, Anil, Katz, Sharyn I, Gillespie, Colin T, Cheng, Guanjun, Sun, Jing, Papasavvas, Emmanouil, Montaner, Luis J, Heitjan, Daniel F, Litzky, Leslie, Friedberg, Joseph, Culligan, Melissa, June, Carl H, Carroll, Richard G, Albelda, Steven M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviruses Clinical trials Gene therapy Interferon Mesothelioma Patients Tomography
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!