Vision preservation during retinal inflammation by anthocyanin-rich bilberry extract: cellular and molecular mechanism

Anthocyanin-rich bilberry extract, a plant-derived antioxidant, has been utilized as a popular supplement for ocular health worldwide. However, it is unclear whether this extract has any biological effect on visual function, and the mechanism for such an effect is completely unknown. In this study,...

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Veröffentlicht in:	Laboratory investigation 2012-01, Vol.92 (1), p.102-109
Hauptverfasser:	Miyake, Seiji, Takahashi, Noriko, Sasaki, Mariko, Kobayashi, Saori, Tsubota, Kazuo, Ozawa, Yoko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals anthocyanin Anthocyanins - pharmacology Biological and medical sciences Biotechnology Endotoxins - toxicity ERG Fundamental and applied biological sciences. Psychology inflammation Investigative techniques, diagnostic techniques (general aspects) Laboratory Medicine Medical sciences Medicine Medicine & Public Health Mice Mice, Inbred C57BL NF-kappa B - antagonists & inhibitors oxidative stress Oxidative Stress - drug effects Pathology photoreceptor Plant Extracts research-article retina Retinitis - drug therapy Retinitis - physiopathology rhodopsin STAT3 Transcription Factor - metabolism Uveitis - drug therapy Vaccinium myrtillus Vision, Ocular - drug effects
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