Mania-like behavior induced by genetic dysfunction of the neuron-specific Na+,K+-ATPase [alpha]3 sodium pump

Bipolar disorder is a debilitating psychopathology with unknown etiology. Accumulating evidence suggests the possible involvement of Na+,K+-ATPase dysfunction in the pathophysiology of bipolar disorder. Here we show that Myshkin mice carrying an inactivating mutation in the neuron-specific Na+,K+-AT...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2011-11, Vol.108 (44), p.18144
Hauptverfasser:	Kirshenbaum, Greer S, Clapcote, Steven J, Duffy, Steven, Burgess, Christian R, Petersen, Janne, Jarowek, Karolina J, Yücel, Yeni H, Cortez, Miguel A, Snead, O Carter, Vilsen, Bente, Peever, John H, Ralph, Martin R, Roder, John C
Format:	Artikel
Sprache:	eng
Schlagworte:	Bipolar disorder Gene expression Lithium Neurons Proteins Rodents
Online-Zugang:	Volltext
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