NF-[kappa]B/STAT3/PI3K signaling crosstalk in iMycE[mu] B lymphoma

Abstract Background: Myc is a well known driver of lymphomagenesis, and Myc-activating chromosomal translocation is the recognized hallmark of Burkitt lymphoma, an aggressive form of non-Hodgkin's lymphoma. We developed a model that mimics this translocation event by inserting a mouse Myc cDNA...

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Veröffentlicht in:	Molecular cancer 2010-01, Vol.9, p.97
Hauptverfasser:	Han, Seong-Su, Yun, Hwakyung, Son, Dong-Ju, Tompkins, Van S, Peng, Liangping, Chung, Seung-Tae, Kim, Joong-Su, Park, Eun-Sung, Janz, Siegfried
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Kinases Lymphoma Medical research Phosphorylation Rodents Signal transduction Studies Tumors
Online-Zugang:	Volltext
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