Chlamydia pneumoniae and coronary artery disease: legitimized linkages?
Chlamydia pneumoniae (Cp) infection in early life may accelerate atherosclerosis over ensuing decades, leading to cardiovascular complications. Cp promotes endothelial dysfunction and may modulate inflammation underlying atherosclerosis. It represents a biologically plausible candidate for the causa...
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Veröffentlicht in: | Expert review of cardiovascular therapy 2003-10, Vol.1 (3), p.367-384 |
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creator | Higgins, John P Higgins, Johanna A Higgins, Patricia M Ahuja, Samir Higgins, Daniel L |
description | Chlamydia pneumoniae (Cp) infection in early life may accelerate atherosclerosis over ensuing decades, leading to cardiovascular complications. Cp promotes endothelial dysfunction and may modulate inflammation underlying atherosclerosis. It represents a biologically plausible candidate for the causation of atherosclerosis. Other infections simultaneously occurring with Cp may result in a synergistic effect to promote atherosclerosis. Studies on the treatment of Cp with antibiotics indicates decreased rates of infection, modulation of inflammation and in some settings, fewer cardiovascular complications. |
doi_str_mv | 10.1586/14779072.1.3.367 |
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Cp promotes endothelial dysfunction and may modulate inflammation underlying atherosclerosis. It represents a biologically plausible candidate for the causation of atherosclerosis. Other infections simultaneously occurring with Cp may result in a synergistic effect to promote atherosclerosis. Studies on the treatment of Cp with antibiotics indicates decreased rates of infection, modulation of inflammation and in some settings, fewer cardiovascular complications.</description><identifier>ISSN: 1477-9072</identifier><identifier>EISSN: 1744-8344</identifier><identifier>DOI: 10.1586/14779072.1.3.367</identifier><identifier>PMID: 15030265</identifier><language>eng</language><publisher>England: Informa Healthcare</publisher><subject>Antibiotics ; Arteriosclerosis ; Atherosclerosis ; Bacterial pneumonia ; Care and treatment ; Causality ; Chlamydia ; Chlamydia infections ; Chlamydia pneumoniae ; Chlamydophila Infections - complications ; Chlamydophila pneumoniae ; Complications and side effects ; Coronary Artery Disease - etiology ; Coronary heart disease ; Drug therapy ; Health aspects ; Heart diseases ; Humans ; Infection ; Inflammation ; pathogen burden ; Pneumonia ; Research Design ; Reviews ; Risk factors</subject><ispartof>Expert review of cardiovascular therapy, 2003-10, Vol.1 (3), p.367-384</ispartof><rights>1993 Harwood Academic Publishers GmbH Printed in the United States of America 1993</rights><rights>COPYRIGHT 2003 Taylor & Francis Group LLC</rights><rights>COPYRIGHT 2003 Expert Reviews Ltd.</rights><rights>Copyright Expert Reviews Ltd. 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Cp promotes endothelial dysfunction and may modulate inflammation underlying atherosclerosis. It represents a biologically plausible candidate for the causation of atherosclerosis. Other infections simultaneously occurring with Cp may result in a synergistic effect to promote atherosclerosis. Studies on the treatment of Cp with antibiotics indicates decreased rates of infection, modulation of inflammation and in some settings, fewer cardiovascular complications.</description><subject>Antibiotics</subject><subject>Arteriosclerosis</subject><subject>Atherosclerosis</subject><subject>Bacterial pneumonia</subject><subject>Care and treatment</subject><subject>Causality</subject><subject>Chlamydia</subject><subject>Chlamydia infections</subject><subject>Chlamydia pneumoniae</subject><subject>Chlamydophila Infections - complications</subject><subject>Chlamydophila pneumoniae</subject><subject>Complications and side effects</subject><subject>Coronary Artery Disease - etiology</subject><subject>Coronary heart disease</subject><subject>Drug therapy</subject><subject>Health aspects</subject><subject>Heart diseases</subject><subject>Humans</subject><subject>Infection</subject><subject>Inflammation</subject><subject>pathogen burden</subject><subject>Pneumonia</subject><subject>Research Design</subject><subject>Reviews</subject><subject>Risk factors</subject><issn>1477-9072</issn><issn>1744-8344</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNks2L1DAYxoso7rp69yRFYfHSmu-0uwcZBl2FBS96Dm_TdCZrmoxJi4x__abMyKroIjm8Ifk970fyFMVzjGrMG_EGMylbJEmNa1pTIR8Up1gyVjWUsYd5n6-r5f6keJLSDUKUtZw-Lk4wRxQRwU-Lq_XWwbjvLZQ7b-YxeAumBN-XOsTgIe5LiJPJobfJQDIXpTMbO9nR_jB96az_ChuT3j4tHg3gknl2jGfFl_fvPq8_VNefrj6uV9eVZpRMlZSsbQWWTSdRL7noeG7XDIzTTjYYeq05ABWdAIap1rQb5MDbnndCdrlhQs-K80PeXQzfZpMmNdqkjXPgTZiTkpgLwjHO4Ot7QUwajhrJ-IK-_AO9CXP0eQzVIoIRlUhk6NUB2oAzyvohTBH0klOtCBWENS2mmar_QuXVm9Hq4M1g8_mKSCIkasT_C36pgA4CHUNK0QxqF-2Y_0lhpBZTqJ-mUFhRlU2RJS-O883daPo7wdEFGbg8AEv9OML3EF2vJti7EIcIXtuk6D3pL35Tbw24aashmrt3_Kf4FtXK1DY</recordid><startdate>20031001</startdate><enddate>20031001</enddate><creator>Higgins, John P</creator><creator>Higgins, Johanna A</creator><creator>Higgins, Patricia M</creator><creator>Ahuja, Samir</creator><creator>Higgins, Daniel L</creator><general>Informa Healthcare</general><general>Taylor & Francis</general><general>Taylor & Francis Group LLC</general><general>Expert Reviews Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7QL</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>20031001</creationdate><title>Chlamydia pneumoniae and coronary artery disease: legitimized linkages?</title><author>Higgins, John P ; 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Cp promotes endothelial dysfunction and may modulate inflammation underlying atherosclerosis. It represents a biologically plausible candidate for the causation of atherosclerosis. Other infections simultaneously occurring with Cp may result in a synergistic effect to promote atherosclerosis. Studies on the treatment of Cp with antibiotics indicates decreased rates of infection, modulation of inflammation and in some settings, fewer cardiovascular complications.</abstract><cop>England</cop><pub>Informa Healthcare</pub><pmid>15030265</pmid><doi>10.1586/14779072.1.3.367</doi><tpages>18</tpages></addata></record> |
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subjects | Antibiotics Arteriosclerosis Atherosclerosis Bacterial pneumonia Care and treatment Causality Chlamydia Chlamydia infections Chlamydia pneumoniae Chlamydophila Infections - complications Chlamydophila pneumoniae Complications and side effects Coronary Artery Disease - etiology Coronary heart disease Drug therapy Health aspects Heart diseases Humans Infection Inflammation pathogen burden Pneumonia Research Design Reviews Risk factors |
title | Chlamydia pneumoniae and coronary artery disease: legitimized linkages? |
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