Chlamydia pneumoniae and coronary artery disease: legitimized linkages?

Chlamydia pneumoniae (Cp) infection in early life may accelerate atherosclerosis over ensuing decades, leading to cardiovascular complications. Cp promotes endothelial dysfunction and may modulate inflammation underlying atherosclerosis. It represents a biologically plausible candidate for the causa...

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Veröffentlicht in:Expert review of cardiovascular therapy 2003-10, Vol.1 (3), p.367-384
Hauptverfasser: Higgins, John P, Higgins, Johanna A, Higgins, Patricia M, Ahuja, Samir, Higgins, Daniel L
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container_end_page 384
container_issue 3
container_start_page 367
container_title Expert review of cardiovascular therapy
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creator Higgins, John P
Higgins, Johanna A
Higgins, Patricia M
Ahuja, Samir
Higgins, Daniel L
description Chlamydia pneumoniae (Cp) infection in early life may accelerate atherosclerosis over ensuing decades, leading to cardiovascular complications. Cp promotes endothelial dysfunction and may modulate inflammation underlying atherosclerosis. It represents a biologically plausible candidate for the causation of atherosclerosis. Other infections simultaneously occurring with Cp may result in a synergistic effect to promote atherosclerosis. Studies on the treatment of Cp with antibiotics indicates decreased rates of infection, modulation of inflammation and in some settings, fewer cardiovascular complications.
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Cp promotes endothelial dysfunction and may modulate inflammation underlying atherosclerosis. It represents a biologically plausible candidate for the causation of atherosclerosis. Other infections simultaneously occurring with Cp may result in a synergistic effect to promote atherosclerosis. 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subjects Antibiotics
Arteriosclerosis
Atherosclerosis
Bacterial pneumonia
Care and treatment
Causality
Chlamydia
Chlamydia infections
Chlamydia pneumoniae
Chlamydophila Infections - complications
Chlamydophila pneumoniae
Complications and side effects
Coronary Artery Disease - etiology
Coronary heart disease
Drug therapy
Health aspects
Heart diseases
Humans
Infection
Inflammation
pathogen burden
Pneumonia
Research Design
Reviews
Risk factors
title Chlamydia pneumoniae and coronary artery disease: legitimized linkages?
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