Lack of [alpha]8 integrin leads to morphological changes in renal mesangial cells, but not in vascular smooth muscle cells

Background Extracellular matrix receptors of the integrin family are known to regulate cell adhesion, shape and functions. The [alpha]8 integrin chain is expressed in glomerular mesangial cells and in vascular smooth muscle cells. Mice deficient for [alpha]8 integrin have structural alterations in g...

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Veröffentlicht in:	BMC cell biology 2010-12, Vol.11, p.102
Hauptverfasser:	Marek, Ines, Volkert, Gudrun, Jahn, Angelika, Fahlbusch, Fabian, Zürn, Christina, Özcan, Zehra, Goppelt-Struebe, Margarete, Hilgers, Karl F, Rascher, Wolfgang, Hartner, Andrea
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell proliferation Cells Cellular signal transduction Experiments Integrins Ligands Muscular system Phenotype Physiological aspects Polyclonal antibodies Rodents Smooth muscle Standard deviation Vascular smooth muscle
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