Topological virtual screening: a way to find new compounds active in ulcerative colitis by inhibiting NF-[kappa]B

Ulcerative colitis and Crohn's disease are chronic, immune-mediated inflammatory diseases of the gastrointestinal tract. Nuclear Factor Kappa B (NF-κB) is a transcription factor that plays a key role in regulating expression of multiple inflammatory and immune genes. In this study, a Topologica...

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Veröffentlicht in:	Molecular diversity 2011-11, Vol.15 (4), p.917
Hauptverfasser:	Gálvez-llompart, María, Recio, María C, García-domenech, Ramón
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical compounds Inflammatory bowel disease Molecular structure Pharmaceutical sciences Proteins
Online-Zugang:	Volltext
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