Detection of KRAS mutations in tumor cells using biochips

Somatic mutations in the KRAS gene are important markers of some types of tumors, for example, pancreatic cancer, and may be useful in early diagnostics. A biochip has been developed which allows deter-mining most frequent mutations in 12, 13, and 61 codons of the KRAS gene. To increase the sensitiv...

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Veröffentlicht in:	Molecular biology (New York) 2011-10, Vol.45 (5), p.797-803
Hauptverfasser:	Emelyanova, M. A., Amossenko, F. A., Chudinov, A. V., Surzhikov, S. A., Kazubskaya, T. P., Lubchenko, L. N., Nasedkina, T. V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomarkers Biomedical and Life Sciences Cellular biology Human Genetics Life Sciences Molecular biology Molecular Biology of the Cell Mutation Tumors
Online-Zugang:	Volltext
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