Scalp cooling in the prevention of alopecia in patients receiving depilating chemotherapy
To assess any difference in the incidence of alopecia during treatment and of skull metastases during follow-up among breast cancer patients undergoing scalp cooling during chemotherapy and those treated at ambient temperatures. A series of 35 breast cancer patients receiving adjuvant chemotherapy w...
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Veröffentlicht in: | Supportive care in cancer 1997-03, Vol.5 (2), p.136-138 |
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description | To assess any difference in the incidence of alopecia during treatment and of skull metastases during follow-up among breast cancer patients undergoing scalp cooling during chemotherapy and those treated at ambient temperatures. A series of 35 breast cancer patients receiving adjuvant chemotherapy were consecutively assigned either to a scalp cooling regimen (19 patients) or to an ambient temperature regimen (16 patients). Hypothermia was administered with electrically cooled caps (SCS II: Amit Technology, Jerusalem) for 1 h after treatment. A significant difference (P = 0.014) was detected in the incidence of alopoecia: 48% (9 patients) of those who had undergone cooling suffered alopoecia, while 81% (13 patients) of the group who had not undergone cooling lost scalp hair. Patient comfort levels were high. Follow-up (median time 14 months) has disclosed no scalp metastases. The implementation of routine scalp hypothermia as part of adjuvant chemotherapy treatment, especially in cancers without tendencies to bone metastases, should be seriously considered. |
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Follow-up (median time 14 months) has disclosed no scalp metastases. The implementation of routine scalp hypothermia as part of adjuvant chemotherapy treatment, especially in cancers without tendencies to bone metastases, should be seriously considered.</description><identifier>ISSN: 0941-4355</identifier><identifier>EISSN: 1433-7339</identifier><identifier>DOI: 10.1007/bf01262571</identifier><identifier>PMID: 9069614</identifier><language>eng</language><publisher>Heidelberg: Springer</publisher><subject>Alopecia - chemically induced ; Alopecia - prevention & control ; Antineoplastic Agents - adverse effects ; Baldness ; Biological and medical sciences ; Breast cancer ; Breast Neoplasms - drug therapy ; Case-Control Studies ; Chemotherapy ; Cooling ; Diseases of the skin. Cosmetics ; Female ; Humans ; Hypothermia, Induced ; Medical sciences ; Patient Satisfaction ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. 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G</creatorcontrib><creatorcontrib>KALMUS, Y</creatorcontrib><creatorcontrib>KALMUS, Z</creatorcontrib><creatorcontrib>INBAR, M</creatorcontrib><creatorcontrib>CHAITCHIK, S</creatorcontrib><title>Scalp cooling in the prevention of alopecia in patients receiving depilating chemotherapy</title><title>Supportive care in cancer</title><addtitle>Support Care Cancer</addtitle><description>To assess any difference in the incidence of alopecia during treatment and of skull metastases during follow-up among breast cancer patients undergoing scalp cooling during chemotherapy and those treated at ambient temperatures. A series of 35 breast cancer patients receiving adjuvant chemotherapy were consecutively assigned either to a scalp cooling regimen (19 patients) or to an ambient temperature regimen (16 patients). Hypothermia was administered with electrically cooled caps (SCS II: Amit Technology, Jerusalem) for 1 h after treatment. A significant difference (P = 0.014) was detected in the incidence of alopoecia: 48% (9 patients) of those who had undergone cooling suffered alopoecia, while 81% (13 patients) of the group who had not undergone cooling lost scalp hair. Patient comfort levels were high. Follow-up (median time 14 months) has disclosed no scalp metastases. The implementation of routine scalp hypothermia as part of adjuvant chemotherapy treatment, especially in cancers without tendencies to bone metastases, should be seriously considered.</description><subject>Alopecia - chemically induced</subject><subject>Alopecia - prevention & control</subject><subject>Antineoplastic Agents - adverse effects</subject><subject>Baldness</subject><subject>Biological and medical sciences</subject><subject>Breast cancer</subject><subject>Breast Neoplasms - drug therapy</subject><subject>Case-Control Studies</subject><subject>Chemotherapy</subject><subject>Cooling</subject><subject>Diseases of the skin. Cosmetics</subject><subject>Female</subject><subject>Humans</subject><subject>Hypothermia, Induced</subject><subject>Medical sciences</subject><subject>Patient Satisfaction</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. 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subjects | Alopecia - chemically induced Alopecia - prevention & control Antineoplastic Agents - adverse effects Baldness Biological and medical sciences Breast cancer Breast Neoplasms - drug therapy Case-Control Studies Chemotherapy Cooling Diseases of the skin. Cosmetics Female Humans Hypothermia, Induced Medical sciences Patient Satisfaction Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Scalp Statistics, Nonparametric |
title | Scalp cooling in the prevention of alopecia in patients receiving depilating chemotherapy |
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