Scalp cooling in the prevention of alopecia in patients receiving depilating chemotherapy

To assess any difference in the incidence of alopecia during treatment and of skull metastases during follow-up among breast cancer patients undergoing scalp cooling during chemotherapy and those treated at ambient temperatures. A series of 35 breast cancer patients receiving adjuvant chemotherapy w...

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Veröffentlicht in:Supportive care in cancer 1997-03, Vol.5 (2), p.136-138
Hauptverfasser: RON, I. G, KALMUS, Y, KALMUS, Z, INBAR, M, CHAITCHIK, S
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container_end_page 138
container_issue 2
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container_title Supportive care in cancer
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creator RON, I. G
KALMUS, Y
KALMUS, Z
INBAR, M
CHAITCHIK, S
description To assess any difference in the incidence of alopecia during treatment and of skull metastases during follow-up among breast cancer patients undergoing scalp cooling during chemotherapy and those treated at ambient temperatures. A series of 35 breast cancer patients receiving adjuvant chemotherapy were consecutively assigned either to a scalp cooling regimen (19 patients) or to an ambient temperature regimen (16 patients). Hypothermia was administered with electrically cooled caps (SCS II: Amit Technology, Jerusalem) for 1 h after treatment. A significant difference (P = 0.014) was detected in the incidence of alopoecia: 48% (9 patients) of those who had undergone cooling suffered alopoecia, while 81% (13 patients) of the group who had not undergone cooling lost scalp hair. Patient comfort levels were high. Follow-up (median time 14 months) has disclosed no scalp metastases. The implementation of routine scalp hypothermia as part of adjuvant chemotherapy treatment, especially in cancers without tendencies to bone metastases, should be seriously considered.
doi_str_mv 10.1007/bf01262571
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subjects Alopecia - chemically induced
Alopecia - prevention & control
Antineoplastic Agents - adverse effects
Baldness
Biological and medical sciences
Breast cancer
Breast Neoplasms - drug therapy
Case-Control Studies
Chemotherapy
Cooling
Diseases of the skin. Cosmetics
Female
Humans
Hypothermia, Induced
Medical sciences
Patient Satisfaction
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Scalp
Statistics, Nonparametric
title Scalp cooling in the prevention of alopecia in patients receiving depilating chemotherapy
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