Interactions among [alpha]-synuclein, dopamine, and biomembranes: Some clues for understanding neurodegeneration in parkinson's disease

Parkinson's disease (PD) is a neurologic disorder resulting from the loss of dopaminergic neurons in the brain. Two lines of evidence suggest that the protein α-synuclein plays a role in the pathogenesis of PD: Fibrillar α-synuclein is a major component of Lewy bodies in diseased neurons, and t...

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Veröffentlicht in:	Journal of molecular neuroscience 2004-02, Vol.23 (1-2), p.23
Hauptverfasser:	Rochet, Jean-christophe, Fleming Outeiro, Tiago, Conway, Kelly A, Ding, Tomas T, Volles, Michael J, Lashuel, Hilal A, Bieganski, Robert M, Lindquist, Susan L, Lansbury, Peter T
Format:	Artikel
Sprache:	eng
Schlagworte:	Dopamine Neurodegeneration Parkinson's disease Proteins
Online-Zugang:	Volltext
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