Osteoclasts in the Dental Microenvironment: A Delicate Balance Controls Dental Histogenesis

The impact of osteoclast activity on dental development has been previously analyzed but in the context of severe osteopetrosis. The present study sought to investigate the effects of osteoclast hypofunction,present in Msx2 gene knockin mutant mice (Msx2–/–), and hyperfunction, in transgenic mice dr...

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Veröffentlicht in:	Cells, tissues, organs tissues, organs, 2011-08, Vol.194 (2-4), p.238-243
Hauptverfasser:	Berdal, A., Castaneda, B., Aïoub, M., Néfussi, J.R., Mueller, C., Descroix, V., Lézot, F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell interactions Cell proliferation Cellular Microenvironment Dental pulp Dental roots Differentiation Epithelium Histogenesis Homeodomain Proteins - metabolism Mandible Mandible - diagnostic imaging Mandible - growth & development Mandible - pathology Mice Mice, Transgenic Microenvironments Molar - diagnostic imaging Molar - growth & development Molar - metabolism Molar - pathology Molars Msx2 protein Mutation - genetics Osteoclasts Osteoclasts - metabolism Osteoclasts - pathology Osteopetrosis Osteoprogenitor cells Overexpression Receptor Activator of Nuclear Factor-kappa B - metabolism Teeth Tooth - diagnostic imaging Tooth - growth & development Tooth - metabolism Tooth - pathology Transgenic mice Tumorigenesis X-Ray Microtomography
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