Atropine-induced rhabdomyolysis: An uncommon and potentially fatal adverse drug reaction
A 25 year old woman received daily injection of 0.6 mg atropine for seven days by the intra-venous route. In addition to fever, incomprehensible speech and alteration of sensorium she developed albuminuria, hemoglobinuria and myoglobinuria. A diagnosis of atropine-induced rhabdomyolysis was made on...
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| Veröffentlicht in: | Journal of postgraduate medicine 2010-01, Vol.56 (1), p.42-43 |
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| container_title | Journal of postgraduate medicine |
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| creator | Akhtar, S Rai, M. K Dutta, T. K Subrahmanyam, D.K.S Adithan, C |
| description | A 25 year old woman received daily injection of 0.6 mg atropine for
seven days by the intra-venous route. In addition to fever,
incomprehensible speech and alteration of sensorium she developed
albuminuria, hemoglobinuria and myoglobinuria. A diagnosis of
atropine-induced rhabdomyolysis was made on the basis of clinical
presentations and investigations. Although, datura poisoning and
intoxication with wild mushrooms are known to result in rhabdomyolysis,
this can be considered to be the first case of atropine-induced
rhabdomyolysis and myoglobinuria. |
| doi_str_mv | 10.4103/0022-3859.62423 |
| format | Article |
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seven days by the intra-venous route. In addition to fever,
incomprehensible speech and alteration of sensorium she developed
albuminuria, hemoglobinuria and myoglobinuria. A diagnosis of
atropine-induced rhabdomyolysis was made on the basis of clinical
presentations and investigations. Although, datura poisoning and
intoxication with wild mushrooms are known to result in rhabdomyolysis,
this can be considered to be the first case of atropine-induced
rhabdomyolysis and myoglobinuria.</description><identifier>ISSN: 0022-3859</identifier><identifier>EISSN: 0972-2823</identifier><identifier>DOI: 10.4103/0022-3859.62423</identifier><identifier>PMID: 20393254</identifier><language>eng</language><publisher>India: Medknow Publications and Staff Society of Seth GS Medical College and KEM Hospital, Mumbai, India</publisher><subject>Adult ; Adverse drug reaction, atropine, rhabdomyolysis ; Anti-Arrhythmia Agents - adverse effects ; Atropine ; Atropine - adverse effects ; Care and treatment ; Case studies ; Causes of ; Complications and side effects ; Development and progression ; Drug-Related Side Effects and Adverse Reactions ; Fatal Outcome ; Female ; Humans ; Rhabdomyolysis ; Rhabdomyolysis - chemically induced</subject><ispartof>Journal of postgraduate medicine, 2010-01, Vol.56 (1), p.42-43</ispartof><rights>Copyright 2010 Journal of Postgraduate Medicine.</rights><rights>COPYRIGHT 2010 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright Medknow Publications & Media Pvt. Ltd. Jan-Mar 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-b461t-1124cd792503fa39e61760243df2df98f37a391bf55ca7990746b056a16d9c0e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904,79172</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20393254$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Akhtar, S</creatorcontrib><creatorcontrib>Rai, M. K</creatorcontrib><creatorcontrib>Dutta, T. K</creatorcontrib><creatorcontrib>Subrahmanyam, D.K.S</creatorcontrib><creatorcontrib>Adithan, C</creatorcontrib><title>Atropine-induced rhabdomyolysis: An uncommon and potentially fatal adverse drug reaction</title><title>Journal of postgraduate medicine</title><addtitle>J Postgrad Med</addtitle><description>A 25 year old woman received daily injection of 0.6 mg atropine for
seven days by the intra-venous route. In addition to fever,
incomprehensible speech and alteration of sensorium she developed
albuminuria, hemoglobinuria and myoglobinuria. A diagnosis of
atropine-induced rhabdomyolysis was made on the basis of clinical
presentations and investigations. Although, datura poisoning and
intoxication with wild mushrooms are known to result in rhabdomyolysis,
this can be considered to be the first case of atropine-induced
rhabdomyolysis and myoglobinuria.</description><subject>Adult</subject><subject>Adverse drug reaction, atropine, rhabdomyolysis</subject><subject>Anti-Arrhythmia Agents - adverse effects</subject><subject>Atropine</subject><subject>Atropine - adverse effects</subject><subject>Care and treatment</subject><subject>Case studies</subject><subject>Causes of</subject><subject>Complications and side effects</subject><subject>Development and progression</subject><subject>Drug-Related Side Effects and Adverse Reactions</subject><subject>Fatal Outcome</subject><subject>Female</subject><subject>Humans</subject><subject>Rhabdomyolysis</subject><subject>Rhabdomyolysis - chemically induced</subject><issn>0022-3859</issn><issn>0972-2823</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>RBI</sourceid><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkc1rHCEYh6W0NGnac2_FkvNs9NVx1t6W0LSFQC8N5CaOH1uXGZ3qTGH_-7rdbEphUVBen5-v8iD0npIVp4TdEALQsHUrVwI4sBfoksgOGlgDe1n3p9ML9KaUHSFUCM5eowsgTDJo-SV63Mw5TSG6JkS7GGdx_ql7m8Z9GvYllE94E_ESTRrHFLGOFk9pdnEOehj22OtZD1jb3y4Xh21etjg7beaQ4lv0yuuhuHdP6xV6uPv84_Zrc__9y7fbzX3Tc0HnhlLgxnYSWsK8ZtIJ2gkCnFkP1su1Z12t0t63rdGdlKTjoiet0FRYaYhjV-jj8d4pp1-LK7PapSXH2lKtJQgglFXm-shs9eBUiD7NWZsxFKM2ALw2lAQq1Zyhti66rIcUnQ-1_B-_OsPXYd0YzNnAzTFgciolO6-mHEad94oSddCpDsLUQZj6q7MmPjx9bulHZ5_5k79_b-hDGqrFZ8LkoNWpuJvqpAf97A_4rqjI</recordid><startdate>20100101</startdate><enddate>20100101</enddate><creator>Akhtar, S</creator><creator>Rai, M. 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K ; Subrahmanyam, D.K.S ; Adithan, C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b461t-1124cd792503fa39e61760243df2df98f37a391bf55ca7990746b056a16d9c0e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Adverse drug reaction, atropine, rhabdomyolysis</topic><topic>Anti-Arrhythmia Agents - adverse effects</topic><topic>Atropine</topic><topic>Atropine - adverse effects</topic><topic>Care and treatment</topic><topic>Case studies</topic><topic>Causes of</topic><topic>Complications and side effects</topic><topic>Development and progression</topic><topic>Drug-Related Side Effects and Adverse Reactions</topic><topic>Fatal Outcome</topic><topic>Female</topic><topic>Humans</topic><topic>Rhabdomyolysis</topic><topic>Rhabdomyolysis - chemically induced</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Akhtar, S</creatorcontrib><creatorcontrib>Rai, M. 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seven days by the intra-venous route. In addition to fever,
incomprehensible speech and alteration of sensorium she developed
albuminuria, hemoglobinuria and myoglobinuria. A diagnosis of
atropine-induced rhabdomyolysis was made on the basis of clinical
presentations and investigations. Although, datura poisoning and
intoxication with wild mushrooms are known to result in rhabdomyolysis,
this can be considered to be the first case of atropine-induced
rhabdomyolysis and myoglobinuria.</abstract><cop>India</cop><pub>Medknow Publications and Staff Society of Seth GS Medical College and KEM Hospital, Mumbai, India</pub><pmid>20393254</pmid><doi>10.4103/0022-3859.62423</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of postgraduate medicine, 2010-01, Vol.56 (1), p.42-43 |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Bioline International |
| subjects | Adult Adverse drug reaction, atropine, rhabdomyolysis Anti-Arrhythmia Agents - adverse effects Atropine Atropine - adverse effects Care and treatment Case studies Causes of Complications and side effects Development and progression Drug-Related Side Effects and Adverse Reactions Fatal Outcome Female Humans Rhabdomyolysis Rhabdomyolysis - chemically induced |
| title | Atropine-induced rhabdomyolysis: An uncommon and potentially fatal adverse drug reaction |
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