Rho-kinase inhibition attenuates calcium-induced contraction in [beta]-escin but not Triton X-100 permeabilized rabbit femoral artery

K^sup +^-depolarization (KCl) of smooth muscle has long been known to cause Ca^sup 2+^-dependent contraction, but only recently has this G protein-coupled receptor (GPCR)-independent stimulus been associated with rhoA kinase (ROCK)-dependent myosin light chain (MLC) phosphatase inhibition and Ca^sup...

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Veröffentlicht in:Journal of muscle research and cell motility 2011-09, Vol.32 (2), p.77
Hauptverfasser: Clelland, Lyndsay J, Browne, Brendan M, Alvarez, Silvina M, Miner, Amy S, Ratz, Paul H
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Sprache:eng
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