Joint pain and arthritis in renal transplant recipients and correlation with cyclosporine therapy
The aim of this study was to determine the prevalence of joint pain and arthritis in renal transplant recipients and to investigate relationships with various laboratory and clinical parameters. Eighty-two patients who underwent renal transplantation (RT) had joint examinations and reported by quest...
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Veröffentlicht in: | Rheumatology international 2003-07, Vol.23 (4), p.159-162 |
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creator | KART-KÖSEOGLU, Hamide YÜCEL, A. E ISIKLAR, I TÜRKER, I AKCALI, Z HABERAL, M |
description | The aim of this study was to determine the prevalence of joint pain and arthritis in renal transplant recipients and to investigate relationships with various laboratory and clinical parameters.
Eighty-two patients who underwent renal transplantation (RT) had joint examinations and reported by questionnaire on levels of joint pain and arthritis. Each individual was then followed by the rheumatology department for 1 year, with joint examination and laboratory tests every 3 months.
Thirty-one of 82 patients (37.8%) complained of joint pain before RT, of whom seven reported pain continuing after the operation. Seventeen of the 82 (20.7%) began to suffer joint pain after RT. Six (7.3%) and three (3.7%) of the 82 patients, respectively, developed arthritis before and after transplantation.
The study showed that joint pain is common before and after RT. In renal transplant recipients, joint pain significantly correlated with serum cyclosporine levels higher than 200 ng/ml. |
doi_str_mv | 10.1007/s00296-002-0283-y |
format | Article |
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Eighty-two patients who underwent renal transplantation (RT) had joint examinations and reported by questionnaire on levels of joint pain and arthritis. Each individual was then followed by the rheumatology department for 1 year, with joint examination and laboratory tests every 3 months.
Thirty-one of 82 patients (37.8%) complained of joint pain before RT, of whom seven reported pain continuing after the operation. Seventeen of the 82 (20.7%) began to suffer joint pain after RT. Six (7.3%) and three (3.7%) of the 82 patients, respectively, developed arthritis before and after transplantation.
The study showed that joint pain is common before and after RT. In renal transplant recipients, joint pain significantly correlated with serum cyclosporine levels higher than 200 ng/ml.</description><identifier>ISSN: 0172-8172</identifier><identifier>EISSN: 1437-160X</identifier><identifier>DOI: 10.1007/s00296-002-0283-y</identifier><identifier>PMID: 12856139</identifier><language>eng</language><publisher>Berlin: Springer</publisher><subject>Adult ; Arthralgia - chemically induced ; Arthralgia - epidemiology ; Arthralgia - etiology ; Arthritis - chemically induced ; Arthritis - epidemiology ; Arthritis - etiology ; Biological and medical sciences ; Child ; Cyclosporine - adverse effects ; Cyclosporine - blood ; Female ; Health risk assessment ; Humans ; Immunosuppressive Agents - adverse effects ; Immunosuppressive Agents - blood ; Kidney Failure, Chronic - complications ; Kidney Failure, Chronic - surgery ; Kidney Transplantation - adverse effects ; Kidneys ; Male ; Medical sciences ; Middle Aged ; Prevalence ; Retrospective Studies ; Transplants & implants</subject><ispartof>Rheumatology international, 2003-07, Vol.23 (4), p.159-162</ispartof><rights>2003 INIST-CNRS</rights><rights>Springer-Verlag 2003</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c354t-c030ce6d937a46bdb53cb2d94378e7cd332ba9f0c4c6f1e9918f1430484d48573</citedby><cites>FETCH-LOGICAL-c354t-c030ce6d937a46bdb53cb2d94378e7cd332ba9f0c4c6f1e9918f1430484d48573</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14984858$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12856139$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>KART-KÖSEOGLU, Hamide</creatorcontrib><creatorcontrib>YÜCEL, A. E</creatorcontrib><creatorcontrib>ISIKLAR, I</creatorcontrib><creatorcontrib>TÜRKER, I</creatorcontrib><creatorcontrib>AKCALI, Z</creatorcontrib><creatorcontrib>HABERAL, M</creatorcontrib><title>Joint pain and arthritis in renal transplant recipients and correlation with cyclosporine therapy</title><title>Rheumatology international</title><addtitle>Rheumatol Int</addtitle><description>The aim of this study was to determine the prevalence of joint pain and arthritis in renal transplant recipients and to investigate relationships with various laboratory and clinical parameters.
Eighty-two patients who underwent renal transplantation (RT) had joint examinations and reported by questionnaire on levels of joint pain and arthritis. Each individual was then followed by the rheumatology department for 1 year, with joint examination and laboratory tests every 3 months.
Thirty-one of 82 patients (37.8%) complained of joint pain before RT, of whom seven reported pain continuing after the operation. Seventeen of the 82 (20.7%) began to suffer joint pain after RT. Six (7.3%) and three (3.7%) of the 82 patients, respectively, developed arthritis before and after transplantation.
The study showed that joint pain is common before and after RT. In renal transplant recipients, joint pain significantly correlated with serum cyclosporine levels higher than 200 ng/ml.</description><subject>Adult</subject><subject>Arthralgia - chemically induced</subject><subject>Arthralgia - epidemiology</subject><subject>Arthralgia - etiology</subject><subject>Arthritis - chemically induced</subject><subject>Arthritis - epidemiology</subject><subject>Arthritis - etiology</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Cyclosporine - adverse effects</subject><subject>Cyclosporine - blood</subject><subject>Female</subject><subject>Health risk assessment</subject><subject>Humans</subject><subject>Immunosuppressive Agents - adverse effects</subject><subject>Immunosuppressive Agents - blood</subject><subject>Kidney Failure, Chronic - complications</subject><subject>Kidney Failure, Chronic - surgery</subject><subject>Kidney Transplantation - adverse effects</subject><subject>Kidneys</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Prevalence</subject><subject>Retrospective Studies</subject><subject>Transplants & implants</subject><issn>0172-8172</issn><issn>1437-160X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpFkE9rwyAYh2VsrF23D7DLkMGObhpNosdR9pfCLhvsJsYYakk1U8vIt59dA738RHneF38PANcE3xOM64eIcSEqlBPhglM0noA5YbRGpMLfp2COSV0gnmMGLmLc4HyvKnwOZqTgZUWomAP17q1LcFDWQeVaqEJaB5tshPkhGKd6mIJycehVxoLRdrDGpfgPax-C6VWy3sFfm9ZQj7r3cfDBOgPT2gQ1jJfgrFN9NFfTuQBfz0-fy1e0-nh5Wz6ukKYlS0hjirWpWkFrxaqmbUqqm6IVuQ43tW4pLRolOqyZrjpihCC8y10x46xlvKzpAtwe9g7B_-xMTHLjdyEXiJJzRmhdYpEhcoB08DEG08kh2K0KoyRY7p3Kg1OZU-6dyjHP3EyLd83WtMeJSWIG7iZARa36LvvSNh45Jnj-Iad_ySWAjQ</recordid><startdate>20030701</startdate><enddate>20030701</enddate><creator>KART-KÖSEOGLU, Hamide</creator><creator>YÜCEL, A. 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E ; ISIKLAR, I ; TÜRKER, I ; AKCALI, Z ; HABERAL, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c354t-c030ce6d937a46bdb53cb2d94378e7cd332ba9f0c4c6f1e9918f1430484d48573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adult</topic><topic>Arthralgia - chemically induced</topic><topic>Arthralgia - epidemiology</topic><topic>Arthralgia - etiology</topic><topic>Arthritis - chemically induced</topic><topic>Arthritis - epidemiology</topic><topic>Arthritis - etiology</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Cyclosporine - adverse effects</topic><topic>Cyclosporine - blood</topic><topic>Female</topic><topic>Health risk assessment</topic><topic>Humans</topic><topic>Immunosuppressive Agents - adverse effects</topic><topic>Immunosuppressive Agents - blood</topic><topic>Kidney Failure, Chronic - complications</topic><topic>Kidney Failure, Chronic - surgery</topic><topic>Kidney Transplantation - adverse effects</topic><topic>Kidneys</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Prevalence</topic><topic>Retrospective Studies</topic><topic>Transplants & implants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KART-KÖSEOGLU, Hamide</creatorcontrib><creatorcontrib>YÜCEL, A. 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E</au><au>ISIKLAR, I</au><au>TÜRKER, I</au><au>AKCALI, Z</au><au>HABERAL, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Joint pain and arthritis in renal transplant recipients and correlation with cyclosporine therapy</atitle><jtitle>Rheumatology international</jtitle><addtitle>Rheumatol Int</addtitle><date>2003-07-01</date><risdate>2003</risdate><volume>23</volume><issue>4</issue><spage>159</spage><epage>162</epage><pages>159-162</pages><issn>0172-8172</issn><eissn>1437-160X</eissn><abstract>The aim of this study was to determine the prevalence of joint pain and arthritis in renal transplant recipients and to investigate relationships with various laboratory and clinical parameters.
Eighty-two patients who underwent renal transplantation (RT) had joint examinations and reported by questionnaire on levels of joint pain and arthritis. Each individual was then followed by the rheumatology department for 1 year, with joint examination and laboratory tests every 3 months.
Thirty-one of 82 patients (37.8%) complained of joint pain before RT, of whom seven reported pain continuing after the operation. Seventeen of the 82 (20.7%) began to suffer joint pain after RT. Six (7.3%) and three (3.7%) of the 82 patients, respectively, developed arthritis before and after transplantation.
The study showed that joint pain is common before and after RT. In renal transplant recipients, joint pain significantly correlated with serum cyclosporine levels higher than 200 ng/ml.</abstract><cop>Berlin</cop><pub>Springer</pub><pmid>12856139</pmid><doi>10.1007/s00296-002-0283-y</doi><tpages>4</tpages></addata></record> |
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subjects | Adult Arthralgia - chemically induced Arthralgia - epidemiology Arthralgia - etiology Arthritis - chemically induced Arthritis - epidemiology Arthritis - etiology Biological and medical sciences Child Cyclosporine - adverse effects Cyclosporine - blood Female Health risk assessment Humans Immunosuppressive Agents - adverse effects Immunosuppressive Agents - blood Kidney Failure, Chronic - complications Kidney Failure, Chronic - surgery Kidney Transplantation - adverse effects Kidneys Male Medical sciences Middle Aged Prevalence Retrospective Studies Transplants & implants |
title | Joint pain and arthritis in renal transplant recipients and correlation with cyclosporine therapy |
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