Oral cisapride for the control of delayed vomiting following high-dose cisplatin

Although combination antiemetics prevent vomiting during the initial 24 h after high-dose (> or =100 mg/m2) cisplatin, many patients experience delayed emesis 24-120 h afterwards despite receiving prophylactic dexamethasone and metoclopramide during this time. Cisapride is a prokinetic agent, whi...

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Veröffentlicht in:	Supportive care in cancer 1999, Vol.7 (1), p.44-46
Hauptverfasser:	PIZZO, B. A, PISTERS, K. M. W, MILLER, V. A, GRANT, S. C, BALTZER, L, HINCKLEY, L, KRIS, M. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Pain - chemically induced Administration, Oral Aged Antiemetics - administration & dosage Antiemetics - adverse effects Antiemetics - therapeutic use Antineoplastic Agents - administration & dosage Antineoplastic Agents - adverse effects Biological and medical sciences Cisapride - administration & dosage Cisapride - adverse effects Cisapride - therapeutic use Cisplatin - administration & dosage Cisplatin - adverse effects Colic - chemically induced Confidence Intervals Dexamethasone - administration & dosage Dexamethasone - therapeutic use Drug Combinations Drug toxicity and drugs side effects treatment Female Follow-Up Studies Gastrointestinal Agents - administration & dosage Gastrointestinal Agents - adverse effects Gastrointestinal Agents - therapeutic use Humans Injections, Intravenous Male Medical sciences Metoclopramide - administration & dosage Metoclopramide - therapeutic use Middle Aged Ondansetron - administration & dosage Ondansetron - therapeutic use Pharmacology. Drug treatments Toxicity: digestive system Vomiting Vomiting - prevention & control
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