Synergetic inhibition of the brain mitochondrial NADH: Ubiquinone oxidoreductase (Complex I) by fatty acids and Ca^sup 2

The NADH:ubiquinone oxidoreductase (respiratory complex I) activity of inside-out pig brain submitochondrial particles is inhibited by endogenous or externally added free fatty acids in time-dependent fashion. The rate and degree of the inhibition is dramatically increased by Ca^sup 2+^. The Ca^sup...

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Veröffentlicht in:	Biochemistry (Moscow) 2011-08, Vol.76 (8), p.968
Hauptverfasser:	Kalashnikov, D S, Grivennikova, V G, Vinogradov, A D
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Brain Calcium Fatty acids Mitochondria Oxidation
Online-Zugang:	Volltext
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