Combined estrogen and ghrelin administration restores number of blood vessels and collagen type I/III ratio in the urethral and anal canal submucosa of old ovariectomized rats

We compare the effects of estrogen and/or ghrelin on vascular counts and collagen I/III ratio of urethral and anal canal submucosa in old vs young-adult ovariectomized rats. Ovariectomized Fisher 344 rats (18 and 3 months old, n = 24 × 2) received 42 daily intraperitoneal 17-ß estradiol (10 μg/kg),...

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Veröffentlicht in:	International Urogynecology Journal 2008-04, Vol.19 (4), p.547-552
Hauptverfasser:	Rizk, Diaa E. E., Hassan, Hazem A., Al-Marzouqi, Ahmed H., Ramadan, Gaber A., Al-Kedrah, Soha S., Daoud, Sayel A., Fahim, Mohamed A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Anal Canal - blood supply Anal Canal - metabolism Animals Canals Collagen Collagen Type I - metabolism Collagen Type III - metabolism Estradiol - administration & dosage Estradiol - pharmacology Female Ghrelin - administration & dosage Ghrelin - pharmacology Gynecology Medicine Medicine & Public Health Mucous Membrane - blood supply Mucous Membrane - metabolism Neovascularization, Physiologic - drug effects Original Article Ovariectomy Rats Rats, Inbred F344 Rodents Urethra - blood supply Urethra - metabolism Urology
Online-Zugang:	Volltext
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