Acute cholecystitis at initial presentation of polyarteritis nodosa

Polyarteritis nodosa (PAN) is a systemic vasculitis of unknown etiology. Although gastrointestinal involvement may be seen in half of the cases of PAN, vasculitis of the gallbladder at the disease onset is a rare presentation. We report a case of a 48-year-old man who was admitted due to acute chole...

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Veröffentlicht in:Clinical rheumatology 2005-12, Vol.24 (6), p.625-627
Hauptverfasser: Fernandes, Sandra Regina Muchinechi, Samara, Adil Muhib, Magalhães, Eduardo Paiva, Sachetto, Zoraida, Metze, Konradin
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container_end_page 627
container_issue 6
container_start_page 625
container_title Clinical rheumatology
container_volume 24
creator Fernandes, Sandra Regina Muchinechi
Samara, Adil Muhib
Magalhães, Eduardo Paiva
Sachetto, Zoraida
Metze, Konradin
description Polyarteritis nodosa (PAN) is a systemic vasculitis of unknown etiology. Although gastrointestinal involvement may be seen in half of the cases of PAN, vasculitis of the gallbladder at the disease onset is a rare presentation. We report a case of a 48-year-old man who was admitted due to acute cholecystitis. He had complained of myalgia, fever and weight loss for about one month prior to admission. At physical examination, mild hypertension and calf pain were noted. He underwent a cholecystectomy; histopathological evaluation disclosed necrotizing vasculitis suggestive of PAN. We emphasize that cholecystitis may be part of the initial presentation of systemic vasculitis.
doi_str_mv 10.1007/s10067-005-1092-y
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subjects Cholecystitis, Acute - complications
Cholecystitis, Acute - diagnosis
Cholecystitis, Acute - surgery
Cyclophosphamide - therapeutic use
Diagnosis, Differential
Drug Therapy, Combination
Gallbladder
Gallbladder - pathology
Gallbladder - surgery
Gallbladder diseases
Glucocorticoids - therapeutic use
Humans
Immunosuppressive Agents - therapeutic use
Male
Middle Aged
Polyarteritis Nodosa - complications
Polyarteritis Nodosa - diagnosis
Polyarteritis Nodosa - drug therapy
Prednisone - therapeutic use
Treatment Outcome
title Acute cholecystitis at initial presentation of polyarteritis nodosa
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