Prospective randomized comparison of oxybutynin, functional electrostimulation, and pelvic floor training for treatment of detrusor overactivity in women
The purpose of this study is to compare the effectiveness of oxybutynin, functional electrostimulation (FES), and pelvic floor training (PFT) for treatment of women with detrusor overactivity. Sixty-four subjects were randomized to oxybutynin ( n = 22), FES ( n = 21), or PFT ( n = 21). Women were...
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| Veröffentlicht in: | International Urogynecology Journal 2008-08, Vol.19 (8), p.1055-1061 |
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| container_title | International Urogynecology Journal |
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| creator | Arruda, Raquel M. Castro, Rodrigo A. Sousa, Gabriela C. Sartori, Marair G. F. Baracat, Edmund C. Girão, Manoel J. B. C. |
| description | The purpose of this study is to compare the effectiveness of oxybutynin, functional electrostimulation (FES), and pelvic floor training (PFT) for treatment of women with detrusor overactivity. Sixty-four subjects were randomized to oxybutynin (
n
= 22), FES (
n
= 21), or PFT (
n
= 21). Women were evaluated before and after completion of 12 weeks of treatment by subjective response, voiding diary, and urodynamic test. There was subjective symptomatic improvement in 77% of the women treated with oxybutynin, 52% with FES, and 76% with PFT. Urgency resolved in 64% of women treated with oxybutynin, 52% with FES, and in 57% with PFT. Urodynamic evaluation was normal in 36% treated with oxybutynin, 57% with FES, and 52% with PFT. Maximum detrusor involuntary contraction pressure decreased in all groups (
p
|
| doi_str_mv | 10.1007/s00192-008-0586-y |
| format | Article |
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n
= 22), FES (
n
= 21), or PFT (
n
= 21). Women were evaluated before and after completion of 12 weeks of treatment by subjective response, voiding diary, and urodynamic test. There was subjective symptomatic improvement in 77% of the women treated with oxybutynin, 52% with FES, and 76% with PFT. Urgency resolved in 64% of women treated with oxybutynin, 52% with FES, and in 57% with PFT. Urodynamic evaluation was normal in 36% treated with oxybutynin, 57% with FES, and 52% with PFT. Maximum detrusor involuntary contraction pressure decreased in all groups (
p
< 0.05). All treatments were equally effective. Subjective reduction of urge-incontinence episodes was associated with symptomatic improvement.</description><identifier>ISSN: 0937-3462</identifier><identifier>EISSN: 1433-3023</identifier><identifier>DOI: 10.1007/s00192-008-0586-y</identifier><identifier>PMID: 18330483</identifier><language>eng</language><publisher>London: Springer-Verlag</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Electric Stimulation Therapy ; Female ; Gynecology ; Humans ; Mandelic Acids - therapeutic use ; Medicine ; Medicine & Public Health ; Middle Aged ; Muscarinic Antagonists - therapeutic use ; Original Article ; Pelvic Floor ; Physical Therapy Modalities ; Prospective Studies ; Urinary Bladder, Overactive - drug therapy ; Urinary Bladder, Overactive - physiopathology ; Urinary Bladder, Overactive - therapy ; Urinary incontinence ; Urodynamics ; Urology</subject><ispartof>International Urogynecology Journal, 2008-08, Vol.19 (8), p.1055-1061</ispartof><rights>International Urogynecology Journal 2008</rights><rights>The International Urogynecological Association 2008</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c435t-4c923416b0fbe222e59e7dea33169a46a7927ab5c7f3a8b77ba6d1c5d116a50b3</citedby><cites>FETCH-LOGICAL-c435t-4c923416b0fbe222e59e7dea33169a46a7927ab5c7f3a8b77ba6d1c5d116a50b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00192-008-0586-y$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00192-008-0586-y$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>315,782,786,27931,27932,41495,42564,51326</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18330483$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Arruda, Raquel M.</creatorcontrib><creatorcontrib>Castro, Rodrigo A.</creatorcontrib><creatorcontrib>Sousa, Gabriela C.</creatorcontrib><creatorcontrib>Sartori, Marair G. F.</creatorcontrib><creatorcontrib>Baracat, Edmund C.</creatorcontrib><creatorcontrib>Girão, Manoel J. B. C.</creatorcontrib><title>Prospective randomized comparison of oxybutynin, functional electrostimulation, and pelvic floor training for treatment of detrusor overactivity in women</title><title>International Urogynecology Journal</title><addtitle>Int Urogynecol J</addtitle><addtitle>Int Urogynecol J Pelvic Floor Dysfunct</addtitle><description>The purpose of this study is to compare the effectiveness of oxybutynin, functional electrostimulation (FES), and pelvic floor training (PFT) for treatment of women with detrusor overactivity. Sixty-four subjects were randomized to oxybutynin (
n
= 22), FES (
n
= 21), or PFT (
n
= 21). Women were evaluated before and after completion of 12 weeks of treatment by subjective response, voiding diary, and urodynamic test. There was subjective symptomatic improvement in 77% of the women treated with oxybutynin, 52% with FES, and 76% with PFT. Urgency resolved in 64% of women treated with oxybutynin, 52% with FES, and in 57% with PFT. Urodynamic evaluation was normal in 36% treated with oxybutynin, 57% with FES, and 52% with PFT. Maximum detrusor involuntary contraction pressure decreased in all groups (
p
< 0.05). All treatments were equally effective. Subjective reduction of urge-incontinence episodes was associated with symptomatic improvement.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Electric Stimulation Therapy</subject><subject>Female</subject><subject>Gynecology</subject><subject>Humans</subject><subject>Mandelic Acids - therapeutic use</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Muscarinic Antagonists - therapeutic use</subject><subject>Original Article</subject><subject>Pelvic Floor</subject><subject>Physical Therapy Modalities</subject><subject>Prospective Studies</subject><subject>Urinary Bladder, Overactive - drug therapy</subject><subject>Urinary Bladder, Overactive - physiopathology</subject><subject>Urinary Bladder, Overactive - therapy</subject><subject>Urinary incontinence</subject><subject>Urodynamics</subject><subject>Urology</subject><issn>0937-3462</issn><issn>1433-3023</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kc9O3DAQxq2qqCy0D9ALsnomZWzH-XOsEFAkpPZAz5aTTFZeJXawnS3pm_C2ON2VOHGyPPP7PnvmI-Qrg-8MoLwKAKzmGUCVgayKbPlANiwXIhPAxUeygVqUmcgLfkrOQtgBQA4SPpFTVgkBeSU25OW3d2HCNpo9Uq9t50bzDzvaunHS3gRnqeupe16aOS7W2EvazzbRzuqB4pCESR_NOA96LV7SZEEnHPampf3gnKfRa5OEW9r_v6COI9q4unYY_RxS1e3R6_ULJi7UWPrXJeQzOen1EPDL8Twnf25vHq9_Zg-_7u6vfzxkbS5kzPK25iJnRQN9g5xzlDWWHWohWFHrvNBlzUvdyLbsha6asmx00bFWdowVWkIjzsm3g-_k3dOMIaqdm30aL6iqYryWklcJYgeoTeMGj72avBm1XxQDtWahDlmolIVas1BL0lwcjedmxO5NcVx-AvgBCKllt-jfXn7f9RWVwpob</recordid><startdate>20080801</startdate><enddate>20080801</enddate><creator>Arruda, Raquel M.</creator><creator>Castro, Rodrigo A.</creator><creator>Sousa, Gabriela C.</creator><creator>Sartori, Marair G. F.</creator><creator>Baracat, Edmund C.</creator><creator>Girão, Manoel J. B. C.</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20080801</creationdate><title>Prospective randomized comparison of oxybutynin, functional electrostimulation, and pelvic floor training for treatment of detrusor overactivity in women</title><author>Arruda, Raquel M. ; Castro, Rodrigo A. ; Sousa, Gabriela C. ; Sartori, Marair G. F. ; Baracat, Edmund C. ; Girão, Manoel J. B. C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c435t-4c923416b0fbe222e59e7dea33169a46a7927ab5c7f3a8b77ba6d1c5d116a50b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Electric Stimulation Therapy</topic><topic>Female</topic><topic>Gynecology</topic><topic>Humans</topic><topic>Mandelic Acids - therapeutic use</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Muscarinic Antagonists - therapeutic use</topic><topic>Original Article</topic><topic>Pelvic Floor</topic><topic>Physical Therapy Modalities</topic><topic>Prospective Studies</topic><topic>Urinary Bladder, Overactive - drug therapy</topic><topic>Urinary Bladder, Overactive - physiopathology</topic><topic>Urinary Bladder, Overactive - therapy</topic><topic>Urinary incontinence</topic><topic>Urodynamics</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Arruda, Raquel M.</creatorcontrib><creatorcontrib>Castro, Rodrigo A.</creatorcontrib><creatorcontrib>Sousa, Gabriela C.</creatorcontrib><creatorcontrib>Sartori, Marair G. 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F.</au><au>Baracat, Edmund C.</au><au>Girão, Manoel J. B. C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prospective randomized comparison of oxybutynin, functional electrostimulation, and pelvic floor training for treatment of detrusor overactivity in women</atitle><jtitle>International Urogynecology Journal</jtitle><stitle>Int Urogynecol J</stitle><addtitle>Int Urogynecol J Pelvic Floor Dysfunct</addtitle><date>2008-08-01</date><risdate>2008</risdate><volume>19</volume><issue>8</issue><spage>1055</spage><epage>1061</epage><pages>1055-1061</pages><issn>0937-3462</issn><eissn>1433-3023</eissn><abstract>The purpose of this study is to compare the effectiveness of oxybutynin, functional electrostimulation (FES), and pelvic floor training (PFT) for treatment of women with detrusor overactivity. Sixty-four subjects were randomized to oxybutynin (
n
= 22), FES (
n
= 21), or PFT (
n
= 21). Women were evaluated before and after completion of 12 weeks of treatment by subjective response, voiding diary, and urodynamic test. There was subjective symptomatic improvement in 77% of the women treated with oxybutynin, 52% with FES, and 76% with PFT. Urgency resolved in 64% of women treated with oxybutynin, 52% with FES, and in 57% with PFT. Urodynamic evaluation was normal in 36% treated with oxybutynin, 57% with FES, and 52% with PFT. Maximum detrusor involuntary contraction pressure decreased in all groups (
p
< 0.05). All treatments were equally effective. Subjective reduction of urge-incontinence episodes was associated with symptomatic improvement.</abstract><cop>London</cop><pub>Springer-Verlag</pub><pmid>18330483</pmid><doi>10.1007/s00192-008-0586-y</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0937-3462 |
| ispartof | International Urogynecology Journal, 2008-08, Vol.19 (8), p.1055-1061 |
| issn | 0937-3462 1433-3023 |
| language | eng |
| recordid | cdi_proquest_journals_881295528 |
| source | MEDLINE; SpringerNature Journals |
| subjects | Adult Aged Aged, 80 and over Electric Stimulation Therapy Female Gynecology Humans Mandelic Acids - therapeutic use Medicine Medicine & Public Health Middle Aged Muscarinic Antagonists - therapeutic use Original Article Pelvic Floor Physical Therapy Modalities Prospective Studies Urinary Bladder, Overactive - drug therapy Urinary Bladder, Overactive - physiopathology Urinary Bladder, Overactive - therapy Urinary incontinence Urodynamics Urology |
| title | Prospective randomized comparison of oxybutynin, functional electrostimulation, and pelvic floor training for treatment of detrusor overactivity in women |
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