MF59 is a safe and potent vaccine adjuvant that enhances protection against influenza virus infection

In preclinical studies, MF59 adjuvant offered improved protection against influenza virus challenge and significantly reduced the viral load in the lungs of challenged mice. In humans, MF59 is a safe and potent vaccine adjuvant that has been licensed in more than 20 countries (Fluad® [Novartis Vacci...

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Veröffentlicht in:	Expert review of vaccines 2007-10, Vol.6 (5), p.699-710
1. Verfasser:	O Hagan, Derek T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - adverse effects Adjuvants, Immunologic - therapeutic use Adjuvants, Pharmaceutic Animals Health aspects Humans improved influenza vaccines Influenza Influenza vaccines Influenza Vaccines - adverse effects Influenza Vaccines - therapeutic use Influenza, Human - immunology Influenza, Human - prevention & control MF59 adjuvant oil-in-water emulsion Orthomyxoviridae - immunology Polysorbates - adverse effects Polysorbates - therapeutic use Prevention Product development Squalene - adverse effects Squalene - therapeutic use vaccine adjuvant
Online-Zugang:	Volltext
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