Effect of Multiple Oral Doses of Linagliptin on the Steady-State Pharmacokinetics of a Combination Oral Contraceptive in Healthy Female Adults

Background: Linagliptin is an oral dipeptidyl peptidase (DPP)-4 inhibitor that has been recently approved for the treatment of type 2 diabetes mellitus. Microgynon® 30 is a combined oral contraceptive pill containing both ethinylestradiol 30 μg and levonorgestrel 150 μg (EE 30 μg/LNG 150 μg). Object...

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Veröffentlicht in:	Clinical drug investigation 2011-09, Vol.31 (9), p.643
Hauptverfasser:	Friedrich, Christian, Port, Andreas, Ring, Arne, Graefe-Mody, Ulrike, Giessmann, Thomas, Iovino, Mario, Woerle, Hans-Juergen
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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