Stabilizing Effect of Propionic Acid Derivative of Anthraquinone-Polyamine Conjugate Incorporated into [alpha]-[Beta] Chimeric Oligonucleotides on the Alternate-Stranded Triple Helix

Two types of anthraquinone conjugates were synthesized as non-nucleosidic oligonucleotide components. These include an anthraquinone derivative conjugated with 2,2-bis(hydroxymethyl)propionic acid and an anthraquinone-polyamine derivative conjugated with 2,2-bis(hydroxymethyl)propionic acid. The con...

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Veröffentlicht in:Bioconjugate chemistry 2011-06, Vol.22 (6), p.1039
Hauptverfasser: Moriguchi, Tomohisa, Azam, A T M Zafrul, Shinozuka, Kazuo
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Sprache:eng
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