Prostate-specific antigen in the cerebrospinal fluid: A marker of local disease

Leptomeningeal involvement from prostate cancer is a rare complication with dismal prognosis. Prostate-specific antigen in the cerebrospinal fluid may be found elevated and can be used as a marker for local disease. We present the case of a patient with prostate cancer and leptomeningeal metastases...

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Veröffentlicht in:	Medical oncology (Northwood, London, England) London, England), 2009-06, Vol.26 (2), p.143-146
Hauptverfasser:	Orphanos, George, Ioannidis, George, Michael, Michael, Kitrou, George
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antimetabolites, Antineoplastic - therapeutic use Cerebrospinal Fluid - cytology Fatal Outcome Hematology Humans Internal Medicine Male Medicine Medicine & Public Health Meningeal Neoplasms - diagnosis Meningeal Neoplasms - drug therapy Meningeal Neoplasms - secondary Methotrexate - therapeutic use Oncology Original Paper Pathology Prostate-Specific Antigen - cerebrospinal fluid Prostatic Neoplasms - diagnosis Prostatic Neoplasms - drug therapy Prostatic Neoplasms - pathology
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Beschreibung
Zusammenfassung:	Leptomeningeal involvement from prostate cancer is a rare complication with dismal prognosis. Prostate-specific antigen in the cerebrospinal fluid may be found elevated and can be used as a marker for local disease. We present the case of a patient with prostate cancer and leptomeningeal metastases who had high levels of prostate-specific antigen in the cerebrospinal fluid.
ISSN:	1357-0560 1559-131X
DOI:	10.1007/s12032-008-9096-5