Novel protein kinase C, nPKC, inhibition of murine bumetanide-sensitive Na+,K+,2Cl- cotransporter BSC1 in Xenopus oocyte

In vitro transcribed RNAs obtained for the absorptive type of Na,K, 2Cl cotransporter BSC1, isoform F, and either of three deletion mutants were injected into oocytes, while oocytes injected with water served as controls. Wild-type cRNA induced a bumetanide-sensitive Rb flux after 18 h which rose to...

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Veröffentlicht in:	Pflügers Archiv 1998-07, Vol.436 (2), p.189-198
Hauptverfasser:	Baekgaard, A, Bindslev, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bumetanide - pharmacology Carrier Proteins - antagonists & inhibitors Carrier Proteins - genetics Carrier Proteins - physiology Enzyme Activation - drug effects Enzyme Inhibitors - pharmacology Female Gene Transfer Techniques Kinases Mice Naphthalenes - pharmacology Oocytes - metabolism Protein Kinase C - antagonists & inhibitors Protein Kinase C - metabolism Proteins Recombinant Proteins Rubidium - metabolism Sodium-Potassium-Chloride Symporters Staurosporine - pharmacology Tetradecanoylphorbol Acetate - pharmacology Xenopus
Online-Zugang:	Volltext
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