Different effects of SNP and GSNO on mitochondrial O^sub 2^^sup .-^/H2O2 production

Sodium Nitroprusside (SNP) and S-Nitrosoglutathione (GSNO) differently affect mitochondrial H2O2 release at Complex-I. mM SNP increases while GSNO decreases the release induced by succinate alone or added on top of NAD-linked substrates. Stimulation likely depends on Nitric Oxide (^sup .^NO) (releas...

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Veröffentlicht in:Journal of bioenergetics and biomembranes 2011-06, Vol.43 (3), p.267
Hauptverfasser: Tessari, Federica, Bortolami, Silvia, Zoccarato, Franco, Alexandre, Adolfo, Cavallini, Lucia
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Sprache:eng
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