A simple method for fabricating artificial kidney stones of different physical properties
A simple method for preparing artificial kidney stones with varying physical properties is described. BegoStone was prepared with a powder-to-water ratio ranging from 15:3 to 15:6. The acoustic properties of the phantoms were characterized using an ultrasound transmission technique, from which the c...
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Veröffentlicht in: | Urolithiasis 2010-08, Vol.38 (4), p.315-319 |
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description | A simple method for preparing artificial kidney stones with varying physical properties is described. BegoStone was prepared with a powder-to-water ratio ranging from 15:3 to 15:6. The acoustic properties of the phantoms were characterized using an ultrasound transmission technique, from which the corresponding mechanical properties were calculated based on elastic wave theory. The measured parameters for BegoStone phantoms of different water contents are: longitudinal wave speed (3,148–4,159 m/s), transverse wave speed (1,813–2,319 m/s), density (1,563–1,995 kg/m
3
), longitudinal acoustic impedance (4.92–8.30 kg/m
2
s), transverse acoustic impedance (2.83–4.63 kg/m
2
s), Young’s modulus (12.9–27.4 GPa), bulk modulus (8.6–20.2 GPa), and shear modulus (5.1–10.7 GPa), which cover the range of corresponding properties reported in natural kidney stones. In addition, diametral compression tests were carried out to determine tensile failure strength of the stone phantoms. BegoStone phantoms with varying water content at preparation have tensile failure strength from 6.9 to 16.3 MPa when tested dry and 3.2 to 7.1 MPa when tested in water-soaked condition. Overall, it is demonstrated that this new BegoStone preparation method can be used to fabricate artificial stones with physical properties matched with those of natural kidney stones of various chemical compositions. |
doi_str_mv | 10.1007/s00240-010-0298-x |
format | Article |
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3
), longitudinal acoustic impedance (4.92–8.30 kg/m
2
s), transverse acoustic impedance (2.83–4.63 kg/m
2
s), Young’s modulus (12.9–27.4 GPa), bulk modulus (8.6–20.2 GPa), and shear modulus (5.1–10.7 GPa), which cover the range of corresponding properties reported in natural kidney stones. In addition, diametral compression tests were carried out to determine tensile failure strength of the stone phantoms. BegoStone phantoms with varying water content at preparation have tensile failure strength from 6.9 to 16.3 MPa when tested dry and 3.2 to 7.1 MPa when tested in water-soaked condition. Overall, it is demonstrated that this new BegoStone preparation method can be used to fabricate artificial stones with physical properties matched with those of natural kidney stones of various chemical compositions.</description><identifier>ISSN: 0300-5623</identifier><identifier>ISSN: 2194-7228</identifier><identifier>EISSN: 1434-0879</identifier><identifier>EISSN: 2194-7236</identifier><identifier>DOI: 10.1007/s00240-010-0298-x</identifier><identifier>PMID: 20652562</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Chemistry, Physical ; Kidney Calculi - chemistry ; Medical Biochemistry ; Medicine ; Medicine & Public Health ; Nephrology ; Phantoms, Imaging ; Symposium Paper ; Tensile Strength ; Urology</subject><ispartof>Urolithiasis, 2010-08, Vol.38 (4), p.315-319</ispartof><rights>Springer-Verlag 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c468t-abc55d684e96ff6b07e6fc86b0a4927f54a7b3c26d61f2b0cfcb698e5bbe9f273</citedby><cites>FETCH-LOGICAL-c468t-abc55d684e96ff6b07e6fc86b0a4927f54a7b3c26d61f2b0cfcb698e5bbe9f273</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20652562$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Esch, Eric</creatorcontrib><creatorcontrib>Simmons, Walter Neal</creatorcontrib><creatorcontrib>Sankin, Georgy</creatorcontrib><creatorcontrib>Cocks, Hadley F.</creatorcontrib><creatorcontrib>Preminger, Glenn M.</creatorcontrib><creatorcontrib>Zhong, Pei</creatorcontrib><title>A simple method for fabricating artificial kidney stones of different physical properties</title><title>Urolithiasis</title><addtitle>Urol Res</addtitle><addtitle>Urol Res</addtitle><description>A simple method for preparing artificial kidney stones with varying physical properties is described. BegoStone was prepared with a powder-to-water ratio ranging from 15:3 to 15:6. The acoustic properties of the phantoms were characterized using an ultrasound transmission technique, from which the corresponding mechanical properties were calculated based on elastic wave theory. The measured parameters for BegoStone phantoms of different water contents are: longitudinal wave speed (3,148–4,159 m/s), transverse wave speed (1,813–2,319 m/s), density (1,563–1,995 kg/m
3
), longitudinal acoustic impedance (4.92–8.30 kg/m
2
s), transverse acoustic impedance (2.83–4.63 kg/m
2
s), Young’s modulus (12.9–27.4 GPa), bulk modulus (8.6–20.2 GPa), and shear modulus (5.1–10.7 GPa), which cover the range of corresponding properties reported in natural kidney stones. In addition, diametral compression tests were carried out to determine tensile failure strength of the stone phantoms. BegoStone phantoms with varying water content at preparation have tensile failure strength from 6.9 to 16.3 MPa when tested dry and 3.2 to 7.1 MPa when tested in water-soaked condition. Overall, it is demonstrated that this new BegoStone preparation method can be used to fabricate artificial stones with physical properties matched with those of natural kidney stones of various chemical compositions.</description><subject>Chemistry, Physical</subject><subject>Kidney Calculi - chemistry</subject><subject>Medical Biochemistry</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Nephrology</subject><subject>Phantoms, Imaging</subject><subject>Symposium Paper</subject><subject>Tensile Strength</subject><subject>Urology</subject><issn>0300-5623</issn><issn>2194-7228</issn><issn>1434-0879</issn><issn>2194-7236</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1UUmLFDEUDqI47egP8CLBi6fSl6WSqoswDG4w4EUPnkKSeunOWFUpk-ph-t-bpsdxAQ_hBb7lLR8hzxm8ZgD6TQHgEhpg9fG-a24fkA2TQjbQ6f4h2YAAaFrFxRl5Uso1ANOq54_JGQfV8gpsyLcLWuK0jEgnXHdpoCFlGqzL0ds1zltq8xpD9NGO9HscZjzQsqYZC02BDjEEzDivdNkdSlWMdMlpwSrB8pQ8CnYs-OyunpOv7999ufzYXH3-8Ony4qrxUnVrY51v20F1EnsVgnKgUQXf1Y-VPdehlVY74bkaFAvcgQ_eqb7D1jnsA9finLw9-S57N-Hg6zjZjmbJcbL5YJKN5m9kjjuzTTdG6JYLKarBqzuDnH7ssaxmisXjONoZ074YLbu-3pAdW738h3md9nmu25lOMyFAC15J7ETyOZWSMdyPwsAcYzOn2EyNzRxjM7dV8-LPHe4Vv3KqBH4ilArNW8y_O__f9Se6P6YF</recordid><startdate>20100801</startdate><enddate>20100801</enddate><creator>Esch, Eric</creator><creator>Simmons, Walter Neal</creator><creator>Sankin, Georgy</creator><creator>Cocks, Hadley F.</creator><creator>Preminger, Glenn M.</creator><creator>Zhong, Pei</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20100801</creationdate><title>A simple method for fabricating artificial kidney stones of different physical properties</title><author>Esch, Eric ; Simmons, Walter Neal ; Sankin, Georgy ; Cocks, Hadley F. ; Preminger, Glenn M. ; Zhong, Pei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c468t-abc55d684e96ff6b07e6fc86b0a4927f54a7b3c26d61f2b0cfcb698e5bbe9f273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Chemistry, Physical</topic><topic>Kidney Calculi - chemistry</topic><topic>Medical Biochemistry</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Nephrology</topic><topic>Phantoms, Imaging</topic><topic>Symposium Paper</topic><topic>Tensile Strength</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Esch, Eric</creatorcontrib><creatorcontrib>Simmons, Walter Neal</creatorcontrib><creatorcontrib>Sankin, Georgy</creatorcontrib><creatorcontrib>Cocks, Hadley F.</creatorcontrib><creatorcontrib>Preminger, Glenn M.</creatorcontrib><creatorcontrib>Zhong, Pei</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Urolithiasis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Esch, Eric</au><au>Simmons, Walter Neal</au><au>Sankin, Georgy</au><au>Cocks, Hadley F.</au><au>Preminger, Glenn M.</au><au>Zhong, Pei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A simple method for fabricating artificial kidney stones of different physical properties</atitle><jtitle>Urolithiasis</jtitle><stitle>Urol Res</stitle><addtitle>Urol Res</addtitle><date>2010-08-01</date><risdate>2010</risdate><volume>38</volume><issue>4</issue><spage>315</spage><epage>319</epage><pages>315-319</pages><issn>0300-5623</issn><issn>2194-7228</issn><eissn>1434-0879</eissn><eissn>2194-7236</eissn><abstract>A simple method for preparing artificial kidney stones with varying physical properties is described. BegoStone was prepared with a powder-to-water ratio ranging from 15:3 to 15:6. The acoustic properties of the phantoms were characterized using an ultrasound transmission technique, from which the corresponding mechanical properties were calculated based on elastic wave theory. The measured parameters for BegoStone phantoms of different water contents are: longitudinal wave speed (3,148–4,159 m/s), transverse wave speed (1,813–2,319 m/s), density (1,563–1,995 kg/m
3
), longitudinal acoustic impedance (4.92–8.30 kg/m
2
s), transverse acoustic impedance (2.83–4.63 kg/m
2
s), Young’s modulus (12.9–27.4 GPa), bulk modulus (8.6–20.2 GPa), and shear modulus (5.1–10.7 GPa), which cover the range of corresponding properties reported in natural kidney stones. In addition, diametral compression tests were carried out to determine tensile failure strength of the stone phantoms. BegoStone phantoms with varying water content at preparation have tensile failure strength from 6.9 to 16.3 MPa when tested dry and 3.2 to 7.1 MPa when tested in water-soaked condition. Overall, it is demonstrated that this new BegoStone preparation method can be used to fabricate artificial stones with physical properties matched with those of natural kidney stones of various chemical compositions.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>20652562</pmid><doi>10.1007/s00240-010-0298-x</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Chemistry, Physical Kidney Calculi - chemistry Medical Biochemistry Medicine Medicine & Public Health Nephrology Phantoms, Imaging Symposium Paper Tensile Strength Urology |
title | A simple method for fabricating artificial kidney stones of different physical properties |
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