Mild Cognitive Impairment
This article reviews the diagnosis of mild cognitive impairment, its implications for the subsequent development of dementia, and potential management strategies. The possible use of imaging and biomarkers to identify persons at high risk is discussed. Foreword This Journal feature begins with a cas...
Gespeichert in:
| Veröffentlicht in: | The New England journal of medicine 2011-06, Vol.364 (23), p.2227-2234 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2234 |
|---|---|
| container_issue | 23 |
| container_start_page | 2227 |
| container_title | The New England journal of medicine |
| container_volume | 364 |
| creator | Petersen, Ronald C |
| description | This article reviews the diagnosis of mild cognitive impairment, its implications for the subsequent development of dementia, and potential management strategies. The possible use of imaging and biomarkers to identify persons at high risk is discussed.
Foreword
This
Journal
feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.
Stage
A 70-year-old woman has been noticing increasing forgetfulness over the past 6 to 12 months. Although she has always had some difficulty recalling the names of acquaintances, she is now finding it difficult to keep track of appointments and recent telephone calls, but the process has been insidious. She lives independently in the community; she drives a car, pays her bills, and is normal in appearance. A mental status examination revealed slight difficulty on delayed recall of four words, but the results were otherwise normal. Does the patient have mild cognitive impairment? How should her case be managed?
The . . . |
| doi_str_mv | 10.1056/NEJMcp0910237 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_871184450</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2371177181</sourcerecordid><originalsourceid>FETCH-LOGICAL-c324t-c79daa0c8c9db465f197feceeabef2e55813076fa8d835fc9bbdaeccf2a672a43</originalsourceid><addsrcrecordid>eNp1jztPwzAUhS0EEqEwMrBVSIyB61dsj6gqUNTCArN149goVfPATpH49wS1AjFwlrt89zs6hJxTuKYgi5un-ePK9WAoMK4OSEYl57kQUBySDIDpXCjDj8lJSmsYQ4XJyMWq3lTTWffW1kP94aeLpsc6Nr4dTslRwE3yZ_s7Ia9385fZQ758vl_Mbpe540wMuVOmQgSnnalKUchAjQreeY-lD8xLqSkHVQTUleYyOFOWFXrnAsNCMRR8Qi533j5271ufBrvutrEdK61WlGohJIxQvoNc7FKKPtg-1g3GT0vBfo-3f8aP_NVeisnhJkRsXZ1-nphgXEswv1zTJNv6dfOP7wuXIWRZ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>871184450</pqid></control><display><type>article</type><title>Mild Cognitive Impairment</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>New England Journal of Medicine</source><creator>Petersen, Ronald C</creator><creatorcontrib>Petersen, Ronald C</creatorcontrib><description>This article reviews the diagnosis of mild cognitive impairment, its implications for the subsequent development of dementia, and potential management strategies. The possible use of imaging and biomarkers to identify persons at high risk is discussed.
Foreword
This
Journal
feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.
Stage
A 70-year-old woman has been noticing increasing forgetfulness over the past 6 to 12 months. Although she has always had some difficulty recalling the names of acquaintances, she is now finding it difficult to keep track of appointments and recent telephone calls, but the process has been insidious. She lives independently in the community; she drives a car, pays her bills, and is normal in appearance. A mental status examination revealed slight difficulty on delayed recall of four words, but the results were otherwise normal. Does the patient have mild cognitive impairment? How should her case be managed?
The . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMcp0910237</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Waltham, MA: Massachusetts Medical Society</publisher><subject>Age ; Aging ; Alzheimer's disease ; Biological and medical sciences ; Cognition & reasoning ; Cognitive ability ; Dementia ; Dementia disorders ; General aspects ; Geriatrics ; Medical sciences ; Memory ; Patients ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry</subject><ispartof>The New England journal of medicine, 2011-06, Vol.364 (23), p.2227-2234</ispartof><rights>Copyright © 2011 Massachusetts Medical Society. All rights reserved.</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c324t-c79daa0c8c9db465f197feceeabef2e55813076fa8d835fc9bbdaeccf2a672a43</citedby><cites>FETCH-LOGICAL-c324t-c79daa0c8c9db465f197feceeabef2e55813076fa8d835fc9bbdaeccf2a672a43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMcp0910237$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJMcp0910237$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24238509$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>Petersen, Ronald C</creatorcontrib><title>Mild Cognitive Impairment</title><title>The New England journal of medicine</title><description>This article reviews the diagnosis of mild cognitive impairment, its implications for the subsequent development of dementia, and potential management strategies. The possible use of imaging and biomarkers to identify persons at high risk is discussed.
Foreword
This
Journal
feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.
Stage
A 70-year-old woman has been noticing increasing forgetfulness over the past 6 to 12 months. Although she has always had some difficulty recalling the names of acquaintances, she is now finding it difficult to keep track of appointments and recent telephone calls, but the process has been insidious. She lives independently in the community; she drives a car, pays her bills, and is normal in appearance. A mental status examination revealed slight difficulty on delayed recall of four words, but the results were otherwise normal. Does the patient have mild cognitive impairment? How should her case be managed?
The . . .</description><subject>Age</subject><subject>Aging</subject><subject>Alzheimer's disease</subject><subject>Biological and medical sciences</subject><subject>Cognition & reasoning</subject><subject>Cognitive ability</subject><subject>Dementia</subject><subject>Dementia disorders</subject><subject>General aspects</subject><subject>Geriatrics</subject><subject>Medical sciences</subject><subject>Memory</subject><subject>Patients</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1jztPwzAUhS0EEqEwMrBVSIyB61dsj6gqUNTCArN149goVfPATpH49wS1AjFwlrt89zs6hJxTuKYgi5un-ePK9WAoMK4OSEYl57kQUBySDIDpXCjDj8lJSmsYQ4XJyMWq3lTTWffW1kP94aeLpsc6Nr4dTslRwE3yZ_s7Ia9385fZQ758vl_Mbpe540wMuVOmQgSnnalKUchAjQreeY-lD8xLqSkHVQTUleYyOFOWFXrnAsNCMRR8Qi533j5271ufBrvutrEdK61WlGohJIxQvoNc7FKKPtg-1g3GT0vBfo-3f8aP_NVeisnhJkRsXZ1-nphgXEswv1zTJNv6dfOP7wuXIWRZ</recordid><startdate>20110609</startdate><enddate>20110609</enddate><creator>Petersen, Ronald C</creator><general>Massachusetts Medical Society</general><scope>IQODW</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope></search><sort><creationdate>20110609</creationdate><title>Mild Cognitive Impairment</title><author>Petersen, Ronald C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c324t-c79daa0c8c9db465f197feceeabef2e55813076fa8d835fc9bbdaeccf2a672a43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Age</topic><topic>Aging</topic><topic>Alzheimer's disease</topic><topic>Biological and medical sciences</topic><topic>Cognition & reasoning</topic><topic>Cognitive ability</topic><topic>Dementia</topic><topic>Dementia disorders</topic><topic>General aspects</topic><topic>Geriatrics</topic><topic>Medical sciences</topic><topic>Memory</topic><topic>Patients</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Petersen, Ronald C</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Applied & Life Sciences</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Petersen, Ronald C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mild Cognitive Impairment</atitle><jtitle>The New England journal of medicine</jtitle><date>2011-06-09</date><risdate>2011</risdate><volume>364</volume><issue>23</issue><spage>2227</spage><epage>2234</epage><pages>2227-2234</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>This article reviews the diagnosis of mild cognitive impairment, its implications for the subsequent development of dementia, and potential management strategies. The possible use of imaging and biomarkers to identify persons at high risk is discussed.
Foreword
This
Journal
feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.
Stage
A 70-year-old woman has been noticing increasing forgetfulness over the past 6 to 12 months. Although she has always had some difficulty recalling the names of acquaintances, she is now finding it difficult to keep track of appointments and recent telephone calls, but the process has been insidious. She lives independently in the community; she drives a car, pays her bills, and is normal in appearance. A mental status examination revealed slight difficulty on delayed recall of four words, but the results were otherwise normal. Does the patient have mild cognitive impairment? How should her case be managed?
The . . .</abstract><cop>Waltham, MA</cop><pub>Massachusetts Medical Society</pub><doi>10.1056/NEJMcp0910237</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 2011-06, Vol.364 (23), p.2227-2234 |
| issn | 0028-4793 1533-4406 |
| language | eng |
| recordid | cdi_proquest_journals_871184450 |
| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine |
| subjects | Age Aging Alzheimer's disease Biological and medical sciences Cognition & reasoning Cognitive ability Dementia Dementia disorders General aspects Geriatrics Medical sciences Memory Patients Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry |
| title | Mild Cognitive Impairment |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-16T01%3A43%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Mild%20Cognitive%20Impairment&rft.jtitle=The%20New%20England%20journal%20of%20medicine&rft.au=Petersen,%20Ronald%20C&rft.date=2011-06-09&rft.volume=364&rft.issue=23&rft.spage=2227&rft.epage=2234&rft.pages=2227-2234&rft.issn=0028-4793&rft.eissn=1533-4406&rft.coden=NEJMAG&rft_id=info:doi/10.1056/NEJMcp0910237&rft_dat=%3Cproquest_cross%3E2371177181%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=871184450&rft_id=info:pmid/&rfr_iscdi=true |