IL-12- and IL-18-Mediated, Nitric Oxide-Induced Apoptosis in TNF-[alpha]-Mediated Osteoclastogenesis of Bone Marrow Cells
TNF-α has been recognized as an important factor for osteoclastogenesis and plays an important role in bone resorption under pathological conditions. IL-12 and IL-18, which are T-cell mediators, are also important inflammatory cytokines. We have reported that IL-12 and IL-18 induce apoptosis in bone...
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Veröffentlicht in: | Calcified tissue international 2011-07, Vol.89 (1), p.65 |
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