Escherichia coli YaeJ protein mediates a novel ribosome‐rescue pathway distinct from SsrA‐ and ArfA‐mediated pathways

Summary Accumulation of stalled ribosomes at the 3′ end of mRNA without a stop codon (non‐stop mRNA) is supposed to be toxic to bacterial cells. Escherichia coli has at least two distinct systems to rescue such stalled ribosomes: SsrA‐dependent trans‐translation and ArfA‐dependent ribosome rescue. C...

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Veröffentlicht in:	Molecular microbiology 2011-05, Vol.80 (3), p.772-785
Hauptverfasser:	Chadani, Yuhei, Ono, Katsuhiko, Kutsukake, Kazuhiro, Abo, Tatsuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino Acid Substitution - genetics Binding sites Carboxylic Ester Hydrolases - genetics Carboxylic Ester Hydrolases - metabolism Cells E coli Escherichia coli - metabolism Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism Gene Dosage Genotype & phenotype Molecular Sequence Data Mutant Proteins - genetics Mutant Proteins - metabolism Mutation Mutation, Missense Peptides Protein Binding Proteins Ribosomes - metabolism RNA, Transfer, Amino Acyl - metabolism RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism Sequence Alignment Sequence Deletion Transfer RNA
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