Controlling protein translocation through nanopores with bio-inspired fluid walls

Synthetic nanopores have been used to study individual biomolecules in high throughput, but their performance as sensors does not match that of biological ion channels. Challenges include control of nanopore diameters and surface chemistry, modification of the translocation times of single-molecule...

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Veröffentlicht in:	Nature nanotechnology 2011-04, Vol.6 (4), p.253-260
Hauptverfasser:	Yusko, Erik C., Johnson, Jay M., Majd, Sheereen, Prangkio, Panchika, Rollings, Ryan C., Li, Jiali, Yang, Jerry, Mayer, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	639/301/54/989 639/925/350/1058 639/925/350/59 Amyloid beta-Peptides - chemistry Amyloid beta-Peptides - metabolism Animals Arthropod Antennae Biomimetic Materials - chemistry Bombyx Chemistry and Materials Science Diffusion Glycerophosphates - chemistry Glycerophosphates - metabolism Insects Ligands Lipid Bilayers - chemistry Lipid Bilayers - metabolism Lipids Materials Science Nanopores Nanotechnology Nanotechnology and Microengineering Pheromones Pores Porosity Prevention Protein Transport Proteins Sensors Silicon nitride Streptavidin - chemistry Streptavidin - metabolism Surface chemistry Translocation
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