Resistant dermatomyositis complicated by tubercular myositis and successfully treated with rituximab
Sir, B-cell depleting monoclonal antibody rituximab (RTX) has been shown to be effective in patients with refractory dermatomyositis (DM). Magnetic resonance imaging (MRI) of the left leg revealed acute myositis and subcutaneous fluid collection in the areas mentioned [Figure 1]. B-cell driven respo...
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| Veröffentlicht in: | Neurology India 2011-03, Vol.59 (2), p.306 |
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| creator | Jois, Ramesh Vasudevan, Nikhila Srinivasan, Pradeep Mehta, Ravindra |
| description | Sir, B-cell depleting monoclonal antibody rituximab (RTX) has been shown to be effective in patients with refractory dermatomyositis (DM). Magnetic resonance imaging (MRI) of the left leg revealed acute myositis and subcutaneous fluid collection in the areas mentioned [Figure 1]. B-cell driven response with clonal expansion, isotype switch ultimately causing altered plasma cell maturation has been observed. |
| doi_str_mv | 10.4103/0028-3886.79163 |
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Magnetic resonance imaging (MRI) of the left leg revealed acute myositis and subcutaneous fluid collection in the areas mentioned [Figure 1]. B-cell driven response with clonal expansion, isotype switch ultimately causing altered plasma cell maturation has been observed.</description><identifier>ISSN: 0028-3886</identifier><identifier>EISSN: 1998-4022</identifier><identifier>DOI: 10.4103/0028-3886.79163</identifier><identifier>PMID: 21483146</identifier><language>eng</language><publisher>India: Medknow Publications on behalf of the Neurological Society of India</publisher><subject>Adult ; Antibodies, Monoclonal, Murine-Derived - therapeutic use ; Care and treatment ; Case studies ; Complications and side effects ; Dermatomyositis ; Dermatomyositis - complications ; Dermatomyositis - therapy ; Diagnosis ; Drug therapy ; Female ; Humans ; Immunotherapy ; Medical treatment ; Patient outcomes ; Risk factors ; Rituximab ; Treatment Outcome ; Tuberculosis ; Tuberculosis - complications ; Tuberculosis - therapy</subject><ispartof>Neurology India, 2011-03, Vol.59 (2), p.306</ispartof><rights>Copyright 2011 Neurology India.</rights><rights>COPYRIGHT 2011 Medknow Publications and Media Pvt. 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| fulltext | fulltext |
| identifier | ISSN: 0028-3886 |
| ispartof | Neurology India, 2011-03, Vol.59 (2), p.306 |
| issn | 0028-3886 1998-4022 |
| language | eng |
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| source | MEDLINE; EZB Electronic Journals Library |
| subjects | Adult Antibodies, Monoclonal, Murine-Derived - therapeutic use Care and treatment Case studies Complications and side effects Dermatomyositis Dermatomyositis - complications Dermatomyositis - therapy Diagnosis Drug therapy Female Humans Immunotherapy Medical treatment Patient outcomes Risk factors Rituximab Treatment Outcome Tuberculosis Tuberculosis - complications Tuberculosis - therapy |
| title | Resistant dermatomyositis complicated by tubercular myositis and successfully treated with rituximab |
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