PPAR[alpha] Expression Protects Male Mice from High Fat-Induced Nonalcoholic Fatty Liver1-3

Emerging evidence suggests that the lack of PPARα enhances hepatic steatosis and inflammation in Ppara-null mice when fed a high-fat diet (HFD). Thus, the aim of this study was to determine whether Ppara-null mice are more susceptible to nonalcoholic steatohepatitis (NASH) than their wild-type (WT)...

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Veröffentlicht in:	The Journal of nutrition 2011-04, Vol.141 (4), p.603
Hauptverfasser:	Abdelmegeed, Mohamed A, Yoo, Seong-Ho, Henderson, Lauren E, Gonzalez, Frank J, Woodcroft, Kimberley J, Song, Byoung-Joon
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Diet Liver Nutrition research Oxidative stress Proteins Rodents
Online-Zugang:	Volltext
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