Women’s perspective of botulinum toxin treatment for overactive bladder symptoms

Introduction and hypothesis This study aimed to evaluate the women’s’ views and expectations about outcomes and complications of botulinum toxin treatment for overactive bladder (OAB) symptoms. Methods Consecutive women with OAB symptoms and detrusor overactivity were requested to fill out a multipl...

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Veröffentlicht in:International Urogynecology Journal 2011-04, Vol.22 (4), p.425-431
Hauptverfasser: Digesu, G. Alessandro, Panayi, Demetri, Hendricken, Caroline, Camarata, Michelle, Fernando, Ruwan, Khullar, Vikram
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container_end_page 431
container_issue 4
container_start_page 425
container_title International Urogynecology Journal
container_volume 22
creator Digesu, G. Alessandro
Panayi, Demetri
Hendricken, Caroline
Camarata, Michelle
Fernando, Ruwan
Khullar, Vikram
description Introduction and hypothesis This study aimed to evaluate the women’s’ views and expectations about outcomes and complications of botulinum toxin treatment for overactive bladder (OAB) symptoms. Methods Consecutive women with OAB symptoms and detrusor overactivity were requested to fill out a multiple choice questionnaire to assess whether they would consider botulinum and what outcomes as well as complications they would find acceptable to undergo this treatment. Results Two hundred sixty-one women, mean age of 58 (range, 38–78) years, were studied. Two hundred twenty-four were treatment-naive women (group A), while 37 were no responders to anticholinergics (group B). Only 49.6% of women in group A and 54% in group B would accept botulinum toxin. No significant differences were found between treatment-naive women and non-responders to anticholinergics ( p  > 0.05). Conclusions Acceptance of botulinum toxin treatment involves a complex interaction of efficacy and possible complications. The balance of these factors changes the acceptability of the treatment.
doi_str_mv 10.1007/s00192-010-1315-x
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Alessandro ; Panayi, Demetri ; Hendricken, Caroline ; Camarata, Michelle ; Fernando, Ruwan ; Khullar, Vikram</creator><creatorcontrib>Digesu, G. Alessandro ; Panayi, Demetri ; Hendricken, Caroline ; Camarata, Michelle ; Fernando, Ruwan ; Khullar, Vikram</creatorcontrib><description>Introduction and hypothesis This study aimed to evaluate the women’s’ views and expectations about outcomes and complications of botulinum toxin treatment for overactive bladder (OAB) symptoms. Methods Consecutive women with OAB symptoms and detrusor overactivity were requested to fill out a multiple choice questionnaire to assess whether they would consider botulinum and what outcomes as well as complications they would find acceptable to undergo this treatment. Results Two hundred sixty-one women, mean age of 58 (range, 38–78) years, were studied. Two hundred twenty-four were treatment-naive women (group A), while 37 were no responders to anticholinergics (group B). Only 49.6% of women in group A and 54% in group B would accept botulinum toxin. No significant differences were found between treatment-naive women and non-responders to anticholinergics ( p  &gt; 0.05). Conclusions Acceptance of botulinum toxin treatment involves a complex interaction of efficacy and possible complications. 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subjects Adult
Aged
Anti-Dyskinesia Agents - adverse effects
Anti-Dyskinesia Agents - therapeutic use
Botulinum Toxins - adverse effects
Botulinum Toxins - therapeutic use
Female
Gynecology
Humans
Medicine
Medicine & Public Health
Middle Aged
Original Article
Patient Acceptance of Health Care - psychology
Patient Acceptance of Health Care - statistics & numerical data
Prospective Studies
Urinary Bladder, Overactive - drug therapy
Urology
title Women’s perspective of botulinum toxin treatment for overactive bladder symptoms
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