Human acute myelogenous leukemia stem cells are rare and heterogeneous when assayed in NOD/SCID/IL2R[gamma]c-deficient mice

Human leukemic stem cells, like other cancer stem cells, are hypothesized to be rare, capable of incomplete differentiation, and restricted to a phenotype associated with early hematopoietic progenitors or stem cells. However, recent work in other types of tumors has challenged the cancer stem cell...

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Veröffentlicht in:	The Journal of clinical investigation 2011-01, Vol.121 (1), p.384
Hauptverfasser:	Sarry, Jean-Emmanuel, Murphy, Kathleen, Perry, Robin, Sanchez, Patricia V, Secreto, Anthony, Keefer, Cathy, Swider, Cezary R, Strzelecki, Anne-Claire, Cavelier, Cindy, Récher, Christian, Mansat-De Mas, Véronique, Delabesse, Eric, Danet-Desnoyers, G, Carroll, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical research Cancer Genotype & phenotype Leukemia Melanoma Stem cells Transplants & implants
Online-Zugang:	Volltext
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