Diabetes mellitus abrogates erythropoietin-induced cardioprotection against ischemic-reperfusion injury by alteration of the RISK/GSK-3[beta] signaling

Recent studies reported cardioprotective effects of erythropoietin (EPO) against ischemia-reperfusion (I/R) injury through activation of the reperfusion injury salvage kinase (RISK) pathway. As RISK has been reported to be impaired in diabetes and insulin resistance syndrome, we examined whether EPO...

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Veröffentlicht in:	Basic research in cardiology 2011-01, Vol.106 (1), p.147
Hauptverfasser:	Ghaboura, Nehmat, Tamareille, Sophie, Ducluzeau, Pierre-henri, Grimaud, Linda, Loufrani, Laurent, Croué, Anne, Tourmen, Yves, Henrion, Daniel, Furber, Alain, Prunier, Fabrice
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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