Near Infrared Luminescent Oxygen Nanosensors with Nanoparticle Matrix Tailored Sensitivity

The development of sensors for noninvasive determination of oxygen levels in live cells and tissues is critical for the understanding of cellular functions, as well as for monitoring the status of disease, such as cancer, and for predicting the efficacy of therapy. We describe such nontoxic, targete...

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Veröffentlicht in:	Analytical chemistry (Washington) 2010-10, Vol.82 (20), p.8446-8455
Hauptverfasser:	Koo Lee, Yong-Eun, Ulbrich, Elyse E, Kim, Gwangseong, Hah, Hoejin, Strollo, Christen, Fan, Wenzhe, Gurjar, Rajan, Koo, SangMan, Kopelman, Raoul
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Biological and medical sciences Calibration Cell Line, Tumor Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Cells Chemistry Exact sciences and technology Fluorescent Dyes - analysis Fundamental and applied biological sciences. Psychology General, instrumentation Humans Hypoxia Microscopy, Electron, Scanning Molecular and cellular biology Molecular Structure Nanoparticles Nanoparticles - analysis Nanoparticles - ultrastructure Oxygen Oxygen - analysis Sensors Tissues
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