Effects of erdosteine on bleomycin-induced lung fibrosis in rats

This study was designed to examine the effects of erdosteine on bleomycin (BLM)-induced lung fibrosis in rats. Thirty-three Sprague-Dawley rats were divided randomly into three groups, bleomycin alone (BLM), bleomycin + erdosteine (BLM + ERD), and saline alone (control). The BLM and BLM + ERD groups...

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Veröffentlicht in:	Molecular and cellular biochemistry 2006-01, Vol.281 (1-2), p.129-137
Hauptverfasser:	Boyaci, Haşim, Maral, Hale, Turan, Gupse, Başyiğit, Ilknur, Dillioğlugil, Meltem O, Yildiz, Füsun, Tugay, Melih, Pala, Ayşe, Erçin, Cengiz
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Lung Injury - chemically induced Acute Lung Injury - drug therapy Acute Lung Injury - pathology Animals Antioxidants Biomarkers Bleomycin - toxicity Bronchoalveolar Lavage Fluid - cytology Histology Histopathology Lungs Male Nitrates Oxidative Stress - physiology Peroxidation Pulmonary Fibrosis - chemically induced Pulmonary Fibrosis - drug therapy Pulmonary Fibrosis - pathology Rats Rats, Sprague-Dawley Rodents Thioglycolates - therapeutic use Thiophenes - therapeutic use
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