Cinnamtannin B-1 from bay wood exhibits antiapoptotic effects in human platelets

Proanthocyanidins, such as cinnamtannin B-1, are polyphenolic compounds with antioxidant activity that induce apoptosis in a number of tumoral cells. We have now investigated the pro- or anti-apoptotic effects of cinnamtannin B-1 in human platelets. Platelet stimulation with thrombin induced cellula...

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Veröffentlicht in:	Apoptosis (London) 2007-03, Vol.12 (3), p.489-498
Hauptverfasser:	Bouaziz, A, Romera-Castillo, C, Salido, S, Linares-Palomino, P. J, Altarejos, J, Bartegi, A, Rosado, J. A, Salido, G. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Anthocyanins - chemistry Anthocyanins - pharmacology Antioxidants Apoptosis Apoptosis - drug effects Blood Platelets - drug effects Blood Platelets - physiology Caspase 3 - metabolism Caspase 9 - metabolism caspase-3 caspase-9 Cell Fractionation Cells Cinnamtannin B-1 Enzyme Activation Humans Hydrogen Peroxide - pharmacology Laurus - chemistry Molecular Structure Oxidants - pharmacology Phosphatidylserines - metabolism Plant Extracts - chemistry Platelets Proanthocyanidins Thrombin - pharmacology Translocation
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