Cytoprotective and antioxidant activity of Rhodiola imbricata against tert-butyl hydroperoxide induced oxidative injury in U-937 human macrophages

The present study reports cytoprotective and antioxidant activity of aqueous and alcoholic extracts of Rhodiola imbricata rhizome on tert-butyl hydroperoxide (tert-BHP) induced cytotoxicity in U-937 human macrophages. There was an increase in cytotoxicity and apoptosis significantly in the presence...

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Veröffentlicht in:	Molecular and cellular biochemistry 2005-07, Vol.275 (1-2), p.1-6
Hauptverfasser:	Kanupriya, Prasad, D, Sai Ram, M, Kumar, R, Sawhney, R C, Sharma, S K, Ilavazhagan, G, Kumar, D, Banerjee, P K
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Antioxidants - therapeutic use Apoptosis Apoptosis - drug effects Aquatic plants Comet Assay Cytoprotection - drug effects Cytotoxicity Flow Cytometry Humans Macrophages - drug effects Membrane Potentials - drug effects Mitochondrial Membranes - drug effects Oxidative Stress - drug effects Oxidizing agents Plant Extracts - isolation & purification Plant Extracts - pharmacology Reactive Oxygen Species - analysis Reactive Oxygen Species - antagonists & inhibitors Reactive Oxygen Species - metabolism Rhizome - chemistry Rhodiola - chemistry tert-Butylhydroperoxide - toxicity U937 Cells
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