Role of Th2 Cells in IgG4-Related Lacrimal Gland Enlargement

Background: Lacrimal gland enlargement (LGE) is one of the characteristics of Mikulicz’s disease (MD). Recently, marked serum IgG4 elevation and infiltration of IgG4-positive plasmacytes in the enlarged exocrine glands have been reported in MD patients. However, little is known about the role of CD4...

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Veröffentlicht in:	International archives of allergy and immunology 2010-01, Vol.152 (Suppl 1), p.47-53
Hauptverfasser:	Kanari, Hiroko, Kagami, Shin-ichiro, Kashiwakuma, Daisuke, Oya, Yoshihiro, Furuta, Shunsuke, Ikeda, Kei, Suto, Akira, Suzuki, Kotaro, Hirose, Koichi, Watanabe, Norihiko, Okamoto, Yoshitaka, Yamamoto, Shuichi, Iwamoto, Itsuo, Nakajima, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Agonists - administration & dosage Adrenergic beta-Agonists - pharmacology Adult Aged Allergens - immunology Asthma Asthma - blood Asthma - metabolism Biological and medical sciences CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - metabolism Cellular biology Chronic obstructive pulmonary disease, asthma Eosinophils - cytology Exocrine glands Female Forced Expiratory Volume - drug effects Forced Expiratory Volume - physiology Fundamental and applied biological sciences. Psychology Fundamental immunology GATA3 Transcription Factor - genetics Gene Expression - genetics Gene Expression - immunology Humans Hypertrophy - immunology Hypertrophy - metabolism Hypertrophy - pathology Immunoglobulin E - blood Immunoglobulin E - immunology Immunoglobulin G - blood Immunoglobulin G - metabolism Immunoglobulins Immunology Immunopathology Interleukin-10 - genetics Interleukin-13 - genetics Interleukin-4 - genetics Interleukin-5 - genetics Interleukins - genetics Lacrimal Apparatus - pathology Leukocyte Count Lymphocytes Male Medical sciences Middle Aged Original Paper Plasma Cells - metabolism Plasma Cells - pathology Pneumology Respiratory Sounds - diagnosis Respiratory Sounds - drug effects Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Th2 Cells - immunology Th2 Cells - metabolism
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