Synthesis and biological characterization of (Z)-9-heptadecenoic and (Z)-6-methyl-9-heptadecenoic acids : Fatty acids with antibiotic activity produced by Pseudozyma flocculosa
Difficulties in isolating and purifying antibiotic fatty acids from culture filtrates of Pseudozyma flocculosa, a biocontrol agent against powdery mildew, have been limiting factors in studying the properties and understanding the mode of action of the biocontrol agent. We report a new protocol for...
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| Veröffentlicht in: | Journal of chemical ecology 2000-04, Vol.26 (4), p.987-1000 |
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| container_title | Journal of chemical ecology |
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| creator | AVIS, T. J BOULANGER, R. R BELANGER, R. R |
| description | Difficulties in isolating and purifying antibiotic fatty acids from culture filtrates of Pseudozyma flocculosa, a biocontrol agent against powdery mildew, have been limiting factors in studying the properties and understanding the mode of action of the biocontrol agent. We report a new protocol for synthesizing (Z)-9-heptadecenoic and for the first time synthesis of (Z)-6-methyl-9-heptadecenoic acids, two antibiotic fatty acids produced by P. flocculosa. This allowed reproducible and quantifiable means of assaying biological activity of the molecules. In these bioassays, both molecules exhibited antifungal activity corresponding to their expected potency. These new developments should facilitate further studies aimed at deciphering the ecological properties of P. flocculosa. [PUBLICATION ABSTRACT] |
| doi_str_mv | 10.1023/A:1005464326573 |
| format | Article |
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| ispartof | Journal of chemical ecology, 2000-04, Vol.26 (4), p.987-1000 |
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| source | SpringerNature Journals |
| subjects | Airborne microorganisms Antibiotics Bacteria Bioassays Biological and medical sciences Biological control Control Fatty acids Fundamental and applied biological sciences. Psychology Fungal plant pathogens Mode of action Phytopathology. Animal pests. Plant and forest protection |
| title | Synthesis and biological characterization of (Z)-9-heptadecenoic and (Z)-6-methyl-9-heptadecenoic acids : Fatty acids with antibiotic activity produced by Pseudozyma flocculosa |
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