Benzo[a]pyrene-dependent activation of transcription factors NF-[kappa]B and AP-1 related to tumor promotion in hepatoma cell cultures

The activation by the carcinogenic polycyclic aromatic hydrocarbon (PAH) benzo[a]pyrene (BP) of transcription factors NF-κB and AP-1 in hepatoma 27 and HepG2 cell cultures was studied. In contrast to the hepatoma HepG2 cells, cytochrome P450 isoforms and Ah-receptor are not expressed in the hepatoma...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemistry (Moscow) 2007-05, Vol.72 (5), p.552
Hauptverfasser:	Bolotina, N A, Gasparian, A V, Dubovaja, T K, Evteev, V A, Kobliakov, V A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aromatic hydrocarbons Cytochrome Polycyclic aromatic hydrocarbons Pyrene
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!