Effects of d -Amphetamine on Task Performance and Social Behavior of Humans in a Residential Laboratory
Six healthy adult male volunteers lived for 11 days in a residential laboratory. Acute effects of d -amphetamine (0, 5, or 10 mg/70 kg) on performance of tasks, social interaction, and self-reports of drug effects were measured. Each day, participants engaged in a 6.5-hr work period and a 6.5-hr rec...
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Veröffentlicht in: | Experimental and clinical psychopharmacology 1997-05, Vol.5 (2), p.130-136 |
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creator | Ward, Amie S Kelly, Thomas H Foltin, Richard W Fischman, Marian W |
description | Six healthy adult male volunteers lived for 11 days in a residential laboratory. Acute effects of
d
-amphetamine (0, 5, or 10 mg/70 kg) on performance of tasks, social interaction, and self-reports of drug effects were measured. Each day, participants engaged in a 6.5-hr work period and a 6.5-hr recreation period. Beverages containing
d
-amphetamine or placebo were consumed daily before the work period and before the recreation period.
d
-Amphetamine increased response rate without affecting accuracy on some tasks.
d
-Amphetamine increased the proportion of time spent engaging in verbal interaction during the first but not the second week of the study. No changes in self-reported drug effects were observed. Thus,
d
-amphetamine improved performance in the absence of stimulant-like subjective effects. This differentiation between performance and subjective effects confirms the importance of determining the effects of drugs on a range of behaviors. |
doi_str_mv | 10.1037/1064-1297.5.2.130 |
format | Article |
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d
-amphetamine (0, 5, or 10 mg/70 kg) on performance of tasks, social interaction, and self-reports of drug effects were measured. Each day, participants engaged in a 6.5-hr work period and a 6.5-hr recreation period. Beverages containing
d
-amphetamine or placebo were consumed daily before the work period and before the recreation period.
d
-Amphetamine increased response rate without affecting accuracy on some tasks.
d
-Amphetamine increased the proportion of time spent engaging in verbal interaction during the first but not the second week of the study. No changes in self-reported drug effects were observed. Thus,
d
-amphetamine improved performance in the absence of stimulant-like subjective effects. This differentiation between performance and subjective effects confirms the importance of determining the effects of drugs on a range of behaviors.</description><identifier>ISSN: 1064-1297</identifier><identifier>EISSN: 1936-2293</identifier><identifier>DOI: 10.1037/1064-1297.5.2.130</identifier><identifier>PMID: 9234049</identifier><language>eng</language><publisher>United States: American Psychological Association</publisher><subject>Adult ; Amphetamines ; Central Nervous System Stimulants - adverse effects ; Central Nervous System Stimulants - pharmacology ; Cognition - drug effects ; Dextroamphetamine - adverse effects ; Dextroamphetamine - pharmacology ; Human ; Humans ; Learning - drug effects ; Male ; Memory - drug effects ; Psychomotor Performance - drug effects ; Social Behavior ; Social Interaction ; Time Perception - drug effects</subject><ispartof>Experimental and clinical psychopharmacology, 1997-05, Vol.5 (2), p.130-136</ispartof><rights>1997 American Psychological Association</rights><rights>1997, American Psychological Association</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a386t-73e683d5b13569a1a5c8b28e90602b49e10693a76fb8059095adb8afd713ca2e3</citedby><orcidid>0000-0001-9202-623X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9234049$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Schuster, Charles R</contributor><creatorcontrib>Ward, Amie S</creatorcontrib><creatorcontrib>Kelly, Thomas H</creatorcontrib><creatorcontrib>Foltin, Richard W</creatorcontrib><creatorcontrib>Fischman, Marian W</creatorcontrib><title>Effects of d -Amphetamine on Task Performance and Social Behavior of Humans in a Residential Laboratory</title><title>Experimental and clinical psychopharmacology</title><addtitle>Exp Clin Psychopharmacol</addtitle><description>Six healthy adult male volunteers lived for 11 days in a residential laboratory. Acute effects of
d
-amphetamine (0, 5, or 10 mg/70 kg) on performance of tasks, social interaction, and self-reports of drug effects were measured. Each day, participants engaged in a 6.5-hr work period and a 6.5-hr recreation period. Beverages containing
d
-amphetamine or placebo were consumed daily before the work period and before the recreation period.
d
-Amphetamine increased response rate without affecting accuracy on some tasks.
d
-Amphetamine increased the proportion of time spent engaging in verbal interaction during the first but not the second week of the study. No changes in self-reported drug effects were observed. Thus,
d
-amphetamine improved performance in the absence of stimulant-like subjective effects. This differentiation between performance and subjective effects confirms the importance of determining the effects of drugs on a range of behaviors.</description><subject>Adult</subject><subject>Amphetamines</subject><subject>Central Nervous System Stimulants - adverse effects</subject><subject>Central Nervous System Stimulants - pharmacology</subject><subject>Cognition - drug effects</subject><subject>Dextroamphetamine - adverse effects</subject><subject>Dextroamphetamine - pharmacology</subject><subject>Human</subject><subject>Humans</subject><subject>Learning - drug effects</subject><subject>Male</subject><subject>Memory - drug effects</subject><subject>Psychomotor Performance - drug effects</subject><subject>Social Behavior</subject><subject>Social Interaction</subject><subject>Time Perception - drug effects</subject><issn>1064-1297</issn><issn>1936-2293</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkFlLxDAQx4Mo3h_AByHom9A1R6886uIFC4rHc5imU7e6bWrSCvvtTdlVFHyagf8xzI-QI84mnMnsnLM0jrhQ2SSZiAmXbIPsciXTSAglN8P-re-QPe_fGOOxVGKbbCshYxarXfJ6VVVoek9tRUsaXTTdHHto6hapbekz-Hf6gK6yroHWIIW2pE_W1LCglziHz9q6MXk7BNnTuqVAH9HXJbb96JlBYR301i0PyFYFC4-H67lPXq6vnqe30ez-5m56MYtA5mkfZRLTXJZJwWWSKuCQmLwQOSqWMlHECsNHSkKWVkXOEsVUAmWRQ1VmXBoQKPfJyaq3c_ZjQN_rNzu4NpzUaXg-5nmSBxNfmYyz3jusdOfqBtxSc6ZHsHoEp0dwOtFCB7Ahc7wuHooGy5_EmmTQz1Y6dKA7vzTg-tos0JvBuYBDd3P4VXb6v_mP6wvTFI2-</recordid><startdate>19970501</startdate><enddate>19970501</enddate><creator>Ward, Amie S</creator><creator>Kelly, Thomas H</creator><creator>Foltin, Richard W</creator><creator>Fischman, Marian W</creator><general>American Psychological Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7RZ</scope><scope>PSYQQ</scope><orcidid>https://orcid.org/0000-0001-9202-623X</orcidid></search><sort><creationdate>19970501</creationdate><title>Effects of d -Amphetamine on Task Performance and Social Behavior of Humans in a Residential Laboratory</title><author>Ward, Amie S ; Kelly, Thomas H ; Foltin, Richard W ; Fischman, Marian W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a386t-73e683d5b13569a1a5c8b28e90602b49e10693a76fb8059095adb8afd713ca2e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adult</topic><topic>Amphetamines</topic><topic>Central Nervous System Stimulants - adverse effects</topic><topic>Central Nervous System Stimulants - pharmacology</topic><topic>Cognition - drug effects</topic><topic>Dextroamphetamine - adverse effects</topic><topic>Dextroamphetamine - pharmacology</topic><topic>Human</topic><topic>Humans</topic><topic>Learning - drug effects</topic><topic>Male</topic><topic>Memory - drug effects</topic><topic>Psychomotor Performance - drug effects</topic><topic>Social Behavior</topic><topic>Social Interaction</topic><topic>Time Perception - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ward, Amie S</creatorcontrib><creatorcontrib>Kelly, Thomas H</creatorcontrib><creatorcontrib>Foltin, Richard W</creatorcontrib><creatorcontrib>Fischman, Marian W</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>APA PsycArticles®</collection><collection>ProQuest One Psychology</collection><jtitle>Experimental and clinical psychopharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ward, Amie S</au><au>Kelly, Thomas H</au><au>Foltin, Richard W</au><au>Fischman, Marian W</au><au>Schuster, Charles R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of d -Amphetamine on Task Performance and Social Behavior of Humans in a Residential Laboratory</atitle><jtitle>Experimental and clinical psychopharmacology</jtitle><addtitle>Exp Clin Psychopharmacol</addtitle><date>1997-05-01</date><risdate>1997</risdate><volume>5</volume><issue>2</issue><spage>130</spage><epage>136</epage><pages>130-136</pages><issn>1064-1297</issn><eissn>1936-2293</eissn><abstract>Six healthy adult male volunteers lived for 11 days in a residential laboratory. Acute effects of
d
-amphetamine (0, 5, or 10 mg/70 kg) on performance of tasks, social interaction, and self-reports of drug effects were measured. Each day, participants engaged in a 6.5-hr work period and a 6.5-hr recreation period. Beverages containing
d
-amphetamine or placebo were consumed daily before the work period and before the recreation period.
d
-Amphetamine increased response rate without affecting accuracy on some tasks.
d
-Amphetamine increased the proportion of time spent engaging in verbal interaction during the first but not the second week of the study. No changes in self-reported drug effects were observed. Thus,
d
-amphetamine improved performance in the absence of stimulant-like subjective effects. This differentiation between performance and subjective effects confirms the importance of determining the effects of drugs on a range of behaviors.</abstract><cop>United States</cop><pub>American Psychological Association</pub><pmid>9234049</pmid><doi>10.1037/1064-1297.5.2.130</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-9202-623X</orcidid></addata></record> |
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source | MEDLINE; EBSCOhost APA PsycARTICLES |
subjects | Adult Amphetamines Central Nervous System Stimulants - adverse effects Central Nervous System Stimulants - pharmacology Cognition - drug effects Dextroamphetamine - adverse effects Dextroamphetamine - pharmacology Human Humans Learning - drug effects Male Memory - drug effects Psychomotor Performance - drug effects Social Behavior Social Interaction Time Perception - drug effects |
title | Effects of d -Amphetamine on Task Performance and Social Behavior of Humans in a Residential Laboratory |
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