Trefoil factors
There is convincing evidence that trefoil factors (TFFs) do play an important role in tumourigenesis. However, their specific roles in cancer are not yet clear. Recently, TFFs have been shown to interfere with crucial biological processes such as cell proliferation, differentiation, apoptosis and an...
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| Veröffentlicht in: | Cellular and molecular life sciences : CMLS 2005-12, Vol.62 (24), p.2910-2915 |
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| container_title | Cellular and molecular life sciences : CMLS |
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| creator | Regalo, G Wright, N A Machado, J C |
| description | There is convincing evidence that trefoil factors (TFFs) do play an important role in tumourigenesis. However, their specific roles in cancer are not yet clear. Recently, TFFs have been shown to interfere with crucial biological processes such as cell proliferation, differentiation, apoptosis and angiogenesis. Research on the function of TFFs and its relationship with specific signal transduction pathways has also advanced significantly. As a consequence, some ideas about the role of TFFs in cancer have started to take shape. The objective of this review is to summarize and discuss current knowledge on the relationship between TFFs and cancer. |
| doi_str_mv | 10.1007/s00018-005-5478-4 |
| format | Article |
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The objective of this review is to summarize and discuss current knowledge on the relationship between TFFs and cancer.</description><identifier>ISSN: 1420-682X</identifier><identifier>EISSN: 1420-9071</identifier><identifier>DOI: 10.1007/s00018-005-5478-4</identifier><language>eng</language><publisher>Basel: Springer Nature B.V</publisher><subject>Angiogenesis ; Apoptosis ; Biological activity ; Cancer ; Cell differentiation ; Cell proliferation ; Gene expression ; Signal transduction ; Tumors ; Wound healing</subject><ispartof>Cellular and molecular life sciences : CMLS, 2005-12, Vol.62 (24), p.2910-2915</ispartof><rights>Birkhäuser Verlag, Basel 2005.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1184-a6d7751063279c91704cd06795548c5c6ccf60185f447ecf1b9d43ff71d5fa333</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27911,27912</link.rule.ids></links><search><creatorcontrib>Regalo, G</creatorcontrib><creatorcontrib>Wright, N A</creatorcontrib><creatorcontrib>Machado, J C</creatorcontrib><title>Trefoil factors</title><title>Cellular and molecular life sciences : CMLS</title><description>There is convincing evidence that trefoil factors (TFFs) do play an important role in tumourigenesis. 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| ispartof | Cellular and molecular life sciences : CMLS, 2005-12, Vol.62 (24), p.2910-2915 |
| issn | 1420-682X 1420-9071 |
| language | eng |
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| source | Springer Nature - Complete Springer Journals; PubMed Central |
| subjects | Angiogenesis Apoptosis Biological activity Cancer Cell differentiation Cell proliferation Gene expression Signal transduction Tumors Wound healing |
| title | Trefoil factors |
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