Presumptive Abortive Human Rabies—Texas, 2009

Holzmann-Pazgal et al describe the clinical course and laboratory findings of an adolescent girl with encephalitis who had not had rabies vaccination and who had been exposed to bats two months before illness. Antibodies to rabies virus were detected in specimens of the girl's serum and cerebro...

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Veröffentlicht in:JAMA : the journal of the American Medical Association 2010-05, Vol.303 (17), p.1690-1693
Hauptverfasser: Holzmann-Pazgal, G, Wanger, A, Degaffe, G, Rose, C, Heresi, G, Amaya, R, Eshofonie, A, Lee-Han, H, Awosika-Olumo, A, Kuzmin, I, Rupprecht, CE
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container_end_page 1693
container_issue 17
container_start_page 1690
container_title JAMA : the journal of the American Medical Association
container_volume 303
creator Holzmann-Pazgal, G
Wanger, A
Degaffe, G
Rose, C
Heresi, G
Amaya, R
Eshofonie, A
Lee-Han, H
Awosika-Olumo, A
Kuzmin, I
Rupprecht, CE
description Holzmann-Pazgal et al describe the clinical course and laboratory findings of an adolescent girl with encephalitis who had not had rabies vaccination and who had been exposed to bats two months before illness. Antibodies to rabies virus were detected in specimens of the girl's serum and cerebrospinal fluid by indirect fluorescent antibody test. However, the presence of rabies virus-neutralizing antibodies was not detected until after she had received single doses of rabies vaccine and human rabies immune globulin. Although the patient required multiple hospitalizations and follow-up visits for recurrent neurologic symptoms, she survived without intensive care. A CDC editorial note is included.
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1538-3598
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source American Medical Association Journals
subjects Encephalitis
Immunization
Medical treatment
Monoclonal antibodies
Rabies
title Presumptive Abortive Human Rabies—Texas, 2009
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