Incidence of Idiosyncratic Drug-Induced Liver Injury Caused by Prescription Drugs

The incidence of drug-induced liver injury (DILI) is not known for most prescription medications. We aimed to estimate the incidence of DILI for commonly prescribed outpatient drugs. To establish a baseline estimate of DILI incidence, we used the estimated incidence (EI) of amoxicillin/clavulanate D...

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Veröffentlicht in:	Drug safety 2025-02, Vol.48 (2), p.151-160
Hauptverfasser:	Chen, Vincent L, Rockey, Don C, Bjornsson, Einar S, Barnhart, Huiman, Hoofnagle, Jay H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Amoxicillin Amoxicillin-Potassium Clavulanate Combination - adverse effects Angiotensin Angiotensin-converting enzyme inhibitors Anti-Bacterial Agents - adverse effects Antibiotics Antiepileptic agents Azathioprine Azithromycin Chemical and Drug Induced Liver Injury - epidemiology Chemical and Drug Induced Liver Injury - etiology Clindamycin Cohort Studies Coronaviruses COVID-19 Diuretics Doxycycline Drugs Enrollments Enzyme inhibitors Expenditures Female Hepatotoxicity Humans Iceland - epidemiology Incidence Liver Male Metformin Middle Aged Minocycline Nitrofurantoin Pandemics Peptidyl-dipeptidase A Population studies Population-based studies Prescription drugs Prescription Drugs - adverse effects Prospective Studies Risk Serotonin Serotonin uptake inhibitors Statins United States - epidemiology Young Adult
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