Switching to biological DMARDs versus cycling among JAK inhibitors in patients with rheumatoid arthritis and with inadequate response to JAK inhibitors: from FIRST registry

ObjectivesThis study aimed to identify characteristics of patients with rheumatoid arthritis (RA) with an inadequate response to Janus kinase inhibitors (JAKi-IR) and evaluate the efficacy and safety of subsequent treatments.MethodsThis study included 434 patients with RA who started JAKi treatment....

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Veröffentlicht in:	Rheumatic & musculoskeletal diseases open 2025-01, Vol.11 (1), p.e004987
Hauptverfasser:	Miyazaki, Yusuke, Nakayamada, Shingo, Tanaka, Hiroaki, Hanami, Kentaro, Fukuyo, Shunsuke, Kubo, Satoshi, Yamaguchi, Ayako, Miyagawa, Ippei, Satoh-Kanda, Yurie, Todoroki, Yasuyuki, Inoue, Yoshino, Ueno, Masanobu, Tanaka, Yoshiya
Format:	Artikel
Sprache:	eng
Schlagworte:	Activities of daily living Biological Therapy Drug dosages Environmental health Kinases Patients Questionnaires Remission (Medicine) Rheumatoid arthritis Rheumatology Therapeutics TNF inhibitors Tumor necrosis factor-TNF
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