6-Amino-7-((4-methoxybenzyl)thio)quinazolin-4(3H)-one

6-Amino-7-((4-methoxybenzyl)thio)quinazolin-4(3H)-one

The titular compound, 6-amino-7-((4-methoxybenzyl)thio)quinazolin-4(3H)-one, was prepared from 7-fluoro-6-nitroquinazolin-4(3H)-one via a nucleophilic aromatic substitution reaction followed by a reduction of the nitro group. Characterization of the target compound via 1H NMR, 13C NMR, and HRMS conf...

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Veröffentlicht in:MolBank 2024-12, Vol.2024 (4), p.M1942
Hauptverfasser: Thapa, Susila, Bolliger, Jeanne L.
Format: Artikel
Sprache:eng
Schlagworte:
Cancer
Ethanol
heterocycles
Leukemia
Lymphoma
Mass spectrometry
NMR
Nuclear magnetic resonance
nucleophilic aromatic substitution
Pharmaceutical sciences
quinazolin-4(3H)-one
quinazoline
reduction
Scientific imaging
Substitution reactions
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Bolliger, Jeanne L.
description The titular compound, 6-amino-7-((4-methoxybenzyl)thio)quinazolin-4(3H)-one, was prepared from 7-fluoro-6-nitroquinazolin-4(3H)-one via a nucleophilic aromatic substitution reaction followed by a reduction of the nitro group. Characterization of the target compound via 1H NMR, 13C NMR, and HRMS confirmed its structure.
doi_str_mv 10.3390/M1942
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subjects Cancer
Ethanol
heterocycles
Leukemia
Lymphoma
Mass spectrometry
NMR
Nuclear magnetic resonance
nucleophilic aromatic substitution
Pharmaceutical sciences
quinazolin-4(3H)-one
quinazoline
reduction
Scientific imaging
Substitution reactions
title 6-Amino-7-((4-methoxybenzyl)thio)quinazolin-4(3H)-one
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